*Introduction Webinar to Population PK (PKPD) modeling* Due to the cancellation of the PAGE conference, IntiQuan is providing its PAGE Population PK/PD modeling workshop as a free webinar.
In contrast to most other PopPK/PD courses the focus is not on NONMEM but on a general approach on a higher level that works in the same way, independently if NONMEM or MONOLIX (or another NLME parameter estimation tool) is used at the back-end. The major topics covered are: · A general dataset format that is easy to program and understand · Data exploration with graphs and summary tables · Defining structural model and parameter estimation settings (including IIV/BSV, covariance, and covariate models) · NLME parameter estimation in NONMEM and MONOLIX · Model evaluation based on goodness-of-fit plots and VPCs · Model simulation · Reporting The main working environment during the webinar will be R. *Target audience* The webinar is intended for people who · have a basic knowledge of PK, PD and data analysis, and wish to extend their knowledge and skills on population PK/PD. · have a good understanding of parameter estimation and wish to extend their knowledge and skills in the direction of nonlinear mixed effect models. · have a good understanding of population PK/PD modeling and would like to learn how such analyses can be conducted in a fully reproducible, script based, manner – from data preparation to generation of the final report. Knowledge of NONMEM and/or MONOLIX is not required. *Webinar objectives* After the webinar, the participants will be able to set up their own NLME workflow in R to: generate and explore the modeling dataset, perform parameter estimation in supported NLME tools, and evaluate parameter estimation results. Furthermore, participants will be able to generate a short report in Microsoft Word. All material and tools to perform the steps in the webinar will be provided. Application to own modeling projects should be feasible after the webinar. *Registration* Registration is free of charge and can be done using the following link: https://zoom.us/webinar/register/WN_CsjwKZIeSUm7QimJZI6nAQ *Webinar material* Information about how to obtain the webinar material and potential preparations will be sent out a week before the Webinar. Best wishes, Henning ________________________________________________________________________________ IntiQuan GmbH Elisabethenstrasse 23 [see map] <https://goo.gl/maps/x5WM2wVdXK8qcn8c6> 4051 Basel, Switzerland Web: www.intiquan.com Tel: +41 76 603 28 06 *Confidentiality Note: *This message is intended solely for the designated recipient(s). It may contain confidential or proprietary information and may be subject to attorney-client privilege or other confidentiality protections. If you are not a designated recipient you may not review, copy or distribute this message. If you receive this in error, please notify the sender by reply e-mail and delete this message. Thank you. *Data Protection & Privacy:* The IntiQuan Data Protection statement applies for all communication. You can view it here: https://www.intiquan.com/data-protection. IntiQuan GmbH | Managing Director: Dr. Henning Schmidt | Trade register: Basel Stadt CH-270.4.004.907-8 | UID: CHE-181.306.905
