There are many large enterprise grade companies running Node.js at various 
capacities.  

Here is a good deck from Jeff Harrell at PalPal that is helpful answering 
your "lessons learned" request 
http://www.slideshare.net/jeharrell/9-antipatterns-for-nodejs-teams 

This is a great blog post with slides done by Netflix on leveraging Node.js 
for A/B 
testing 
http://techblog.netflix.com/2014/08/scaling-ab-testing-on-netflixcom-with_18.html

Also this is a good article published that highlights very large companies 
that have adopted 
Node.js 
https://developer.salesforce.com/blogs/developer-relations/2014/09/explosive-growth-javascript-npm-enterprise.html

Hope this helps. 
@ryan_stevens

On Wednesday, September 17, 2014 2:50:08 PM UTC-7, Bruno Jouhier wrote:
>
> We (Sage) have been using node.js heavily in the new version of our mid 
> market ERP product (Sage ERP X3 V7). This is not "large enterprise", rather 
> mid-market but the fact that node has been chosen by an ERP vendor may help 
> you sell your story. 
>
> Bruno
>
> On Tuesday, September 16, 2014 11:21:25 PM UTC+2, manwood wrote:
>>
>> I'm looking to build a case for using NodeJs at work (a fairly 
>> conservative and risk averse environment). 
>>
>> Can people point me to any examples of large enterprises, or high traffic 
>> web applications, using currently NodeJs? 
>>
>> Ideally I'm looking for blogs or discussions around proper, real-world 
>> architectures and tech stacks, any problems they've overcome, lessons 
>> learned, stories from the trenches etc. 
>>
>> I have seen FogCreek's Trello for example - I'm looking for more like 
>> this.
>>
>> Thanks
>>
>

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