Anyone who runs Vipre Enterprise should make sure to update to 5475. 5474 is quarantining winlogon.exe and blue screening computers. Check out http://supportforums.sunbeltsoftware.com/messageview.aspx?catid=27&threadid=1802&enterthread=y plus it has happened to me on one system so far. Sunbelt is working on this as I type this.
~ Finally, powerful endpoint security that ISN'T a resource hog! ~ ~ <http://www.sunbeltsoftware.com/Business/VIPRE-Enterprise/> ~