On Nov 17, 2011, at 1:22 PM, Andrew Dalke wrote:

> # In Open Babel 2.3.0, OBConversion() must be called before trying to
> # find any plugin. This was not needed in earlier releases.
> ob.OBConversion()

There's a patch under discussion that would eliminate this for 2.4. Basically, 
we switched fingerprints and other plugins over to be loaded separately, rather 
than compiled into the gigantic libopenbabel. Obviously, the drawback is the 
need for an OBConversion object.

-Geoff
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