I've been studying many open source medical programs, and it seems to me
there are many niche applications but little common infrastructure.  I
believe that in order for any open source projects to become widely
adopted by mainstream physicians, there needs to be a certain level of
interoperability between them (not at the applications level via
standardized interfaces, but at the knowledge level).  I feel there are
certain pieces to the puzzle that would provide a substantial boost to
the open source movement if they became freely available as
international standards, or even de facto standards.  For example:

1.  Pharmacopoeia with drug dosage, interactions, warnings, clinical
pharmacology, etc.

2.  Clinical Concept Knowledge Base modeled using Galen, GEHR
archetypes, "fils guides", etc. with linkages to standard terminologies
and code-sets (i.e. SNOMED, ICD, CPT, READ, etc.)

3.  Clinical Guideline Knowledge Base for workflow modeled using GLIF,
PROforma, PRODIGY, EON, etc.

Perhaps it is the responsibility of governments to fund the development
of such open infrastructures?  I am especially shocked that no
government has forced drug companies to contribute to an international
repository of information on their drugs.  In the US the FDA has
produced a catalog of all approved drugs but as far as I know it
provides no clinically relevant information.  

Perhaps I have a narrow view of what is really going on with regard to
open source medical informatics infrastructure.  Your thoughts on this
matter are greatly appreciated. 

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Matias Klein
HealthNetworks.com


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