Increased Risk of Cow Milk Allergy After Cesarean Delivery

Reuters Health Information 2005. © 2005 Reuters Ltd.
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By Will Boggs, MD

NEW YORK (Reuters Health) Sept 13 - Children delivered by cesarean section face twice the risk of cow milk allergy or intolerance than other children, according to a report in the September issue of Allergy.

"If the findings are confirmed and the underlying mechanism is shown to be tied to an altered intestinal microbial flora, this would open up very exciting future possibilities of treatment of allergic diseases," Dr. Merete Eggesboe from Norwegian Institute of Public Health, Oslo, told Reuters Health.

Dr. Eggesboe and associates, who previously reported a similar association between cesarean section and egg, fish, and nut allergy, investigated possible links between cesarean delivery and cow milk allergy/intolerance in 2656 participants in the Oslo Birth Cohort.

Although there was no association between mode of delivery and parentally perceived reactions to milk, the authors report, cow milk allergy/intolerance was twice as common among children delivered by cesarean section compared to children delivered vaginally.

None of the children previously diagnosed with milk allergy/intolerance but deemed tolerant by age 2.5 years had been delivered by cesarean section, the researchers note, suggesting a negative association between becoming tolerant and cesarean section.

"The results of the present study cannot be explained by differences between predisposed and not predisposed children and thus provides support for early intestinal colonization playing a role in the etiology of food allergy," the investigators conclude.

"We have started a study on the intestinal microflora in children, relating it to mode of delivery and development of allergic diseases," Dr. Eggesboe said. "The aim is to study whether any of the observed differences in intestinal microflora tied to mode of delivery, is also associated with subsequent development of allergic disease."

Allergy 2005;60:1172-1173.

Leanne Wynne
Midwife in charge of "Women's Business"
Mildura Aboriginal Health Service  Mob 0418 371862


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