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>From: "Magyartoto Tersiawan" <[EMAIL PROTECTED]>
>Reply-To: [EMAIL PROTECTED]
>To: "PB List Member"  <[EMAIL PROTECTED]>
>Subject: [PB] OSHA TECHNICAL MANUAL HOSPITAL INVESTIGATIONS: HEALTH HAZARDS 
>{01}
>Date: Fri, 20 Jul 2001 11:47:17 +0700
>
>OSHA TECHNICAL MANUAL
>
>HOSPITAL INVESTIGATIONS: HEALTH HAZARDS
>
>Contents:
>
>       I.
>       II.
>       III.
>       IV.
>       V.
>      Introduction
>       Typical Hazards and Health Effects
>       Investigation Guidelines
>       Controls and Prevention
>       Bibliography
>
>
>Appendix VI:1-1. Biological Agents--Blood and Body Fluids
>Appendix VI:1-2. Chemical Agents
>Appendix VI:1-3. Physical Agents
>
>
>
>   a.. INTRODUCTION.
>     a.. INCIDENCE AND CAUSAL FACTORS. As of 1988, 4% of the total U.S. 
>work force was employed by hospitals. The National Safety Council (NSC) 
>reports that hospital employees are 41% more likely to need time off due to 
>injury or illness than employees in other industries.
>     A survey of 165 clinical laboratories in Minnesota showed that the 
>most frequent type of injuries were needle sticks (63%) followed by cuts 
>and scrapes (21%). Hospital workers frequently report stress as a 
>predisposing factor for accidents. Sprains and strains (often representing 
>low back injury) were the most common type of workers compensation claim in 
>1983 as reported by the Bureau of Labor Statistics. See Chapter VII:1 for 
>more information.
>
>     b.. GUIDANCE. In 1988, NIOSH published Guidelines for Protecting the 
>Safety and Health of Health Care Workers; the American Association of 
>Critical-Care Nurses has published a handbook on the occupational hazards 
>encountered in the critical care environment; and the NSC has a Safety 
>Guide for hospital environments.
>   The hazards of exposure to waste, anesthetic gases, cytotoxic drugs, and 
>blood-borne diseases such as hepatitis and HIV/AIDS are the subject of 
>NIOSH criteria documents and OSHA policy statements.
>
>   b.. TYPICAL HAZARDS AND HEALTH EFFECTS.
>   This chapter covers hospital or health care facility-specific employee 
>hazards. Biological, chemical and physical agents presenting potential 
>exposure to health care employees are reviewed in Appendices VI:1-1 through 
>VI:1-3. These lists are not inclusive.
>
>   c.. INVESTIGATION GUIDELINES.
>     a.. HOSPITAL RECORDS. Hospital's OSHA 200 Log versus employee medical 
>clinic care of employees-is there a possible trend in injuries and 
>illnesses related to typical hazards? If available, check the hospital's 
>safety program records and facility-enabling or operation equipment 
>licenses, e.g., NRC radioisotope and radiation-source license.
>     b.. HOSPITAL SAFETY PROGRAM.
>       1.. Note any previous health and safety inspections by local health 
>departments, fire departments, regulatory or accrediting agencies, such as 
>the Joint Commission on Accreditation of Healthcare Organizations (JCAHO), 
>College of American Pathologists (CAP), and the American Osteopathic 
>Association (AOA).
>       2.. The policies and procedures should outline the training that all 
>employees must receive. General hospital training should include fire and 
>electrical safety, infection control procedures, and the hazard 
>communication program. The policies and procedures should also delineate 
>appropriate personnel and methods for preparation, mixing, application, 
>storage, removal, and disposal of any hazardous agents. Emergency 
>procedures should include provisions for fires, chemical or radioactive 
>spills, extensive blood or body fluid spills, release of compressed, toxic, 
>and corrosive gases, and power failure.
>       3.. A safety committee and/or infection control committee should be 
>established within the hospital. Periodic inspection and monitoring is the 
>responsibility of the safety committee. Immunizations, other than the 
>mandatory vaccination for Hepatitis B, should be offered to personnel at 
>risk.
>       4.. All electrical equipment used in the hospital must be approved 
>for safety by Underwriters Laboratory (UL) or another OSHA-approved body.
>       5.. Biosafety cabinets should be labeled and certified by the 
>manufacturer and/or a safety officer. The cabinets should be placed in the 
>room at a position where doors, windows, and traffic flow will not create 
>turbulence around the face of the cabinet.
>     c.. WALKAROUND: INFORMAL INTERVIEWS. The worker interviews should 
>concentrate on compliance with appropriate policies and procedures. The 
>employee should be able to verbalize what actions to take in the event of 
>an emergency, i.e., accidental chemical or radioactive spill.
>The employee should be aware of the hazards of the products with which he 
>or she works.
>
>Observe the employees' lifting practices. Observe the Walkaround Inspection 
>for Health Hazards. Table VI:1-1 contains a suggested area checklist.
>
>TABLE VI:1-1. WALKAROUND INSPECTION FOR HEALTH HAZARDS
>
>
>
>       Area
>
>
>--------------------------------------------------------------------------
>      To check
>
>
>--------------------------------------------------------------------------
>
>       Every Area
>      Floor slipperiness
>       Adequate marking of hazards and chemical labeling
>       Handling of infectious and chemical wastes
>       Spill and emergency procedures
>       Use of appropriate personal protective equipment
>       Adequate hand-washing facilities
>       Presence of impervious containers for needles and other sharp 
>objects
>       Where equipped, the aerator and local exhaust ventilation for 
>ethylene oxide sterilizers, along with any sampling or vapor badge records
>       Where equipped, the steam autoclave drain should be free of debris
>       Electrical equipment and wiring must meet electrical standards
>
>       Pharmacy
>      Availability of a class II type A or B biological safety cabinet for 
>mixing chemotherapeutic drugs
>       Accurate, clear labels on all drugs, chemicals, and biologicals
>
>       Laboratory
>      Uncluttered work areas, clear ventilation slots, and properly labeled 
>ductwork in laboratory hoods and biological safety cabinets
>       Specimen handling
>       Use of pipettes (no mouth pipetting)
>       Gas cylinder placement and storage
>       Maintenance records for laboratory hoods and other equipment
>       Centrifuge tubes with caps
>       Food should never be stored in refrigerators with lab specimens
>       Readily detectable vapors, fumes, or dust
>       Laser or radiation hazards
>
>       Operating room
>      Handling of waste anesthetic gases
>       Air conditioning and humidity (should be about 50%)
>       Static electricity control
>
>       Radiation area
>      Level of radiation
>       Maintenance and radiation logs
>
>
>
>
>     a..
>
>     a..
>     b.. SCREENING SAMPLES. All sampling is based on the CSHO's 
>professional judgment.
>       a.. SAMPLING METHODS.
>       2.. When sampling, it is important to ensure that it is a typical 
>day, i.e. normal exposure time.
>       3.. Bioaerosols can be evaluated using the ACGIH Bioaerosol 
>Committee's Guidelines. These guidelines contain information on sampling, 
>analysis, and recommendations for remedial actions. Hospital infection 
>control personnel should assist in bioaerosol determinations, as this is 
>nonroutine sampling and is specific for preidentified organisms. 
>Specialized bioaerosol sampling equipment is available through the OSHA 
>Health Response Team.
>       4.. Some of the most commonly found chemicals, e.g., formaldehyde, 
>xylene, halothane, and acrylamide, can be screened using detector tubes. 
>For nitrous oxide, passive monitors can be used to monitor exposure as 
>stated in OSHA Method No. ID-166. Specific sampling for chemical agents, 
>such as ethylene oxide, methyl methacrylate, ribavirin, nitrous oxide, 
>halothane, and other waste anesthetic gases, can be found in the Chemical 
>Information Manual.
>       e.. Lasers are calibrated by the manufacturer, but the laser system 
>must be checked prior to each procedure and during extended procedures. 
>Classifications of lasers must coincide with actual measurement of output 
>(See Figure VI:1-1). Generally, measurements are required when the 
>manufacturer's information is not available, when the laser system has not 
>been classified or when alterations have been made to the laser system that 
>may have changed its classification. Measurements should only be made by 
>personnel trained in laser technology.
>       f.. Records of alignment and power density can be checked against 
>the manufacturer's equipment specifications. Maximum Permissible Exposure 
>(MPE) values to the eyes and skin are given in tables 5, 6, and 7 of the 
>ANSI standard (Z136.1-1986) as well as the ACGIH standard. Requirements for 
>measurements and criteria for calculating the MPE's are given in sections 8 
>and 9 of the ANSI standard.
>       g.. With regard to X-ray machines, film badges or their equivalent 
>should be used for long-term monitoring. Ionizing radiation 
>(x-ray)-Screening of radiation levels may be performed by using 
>thermoluminescence detectors, pocket dosimeters, and Geiger-Mueller 
>counters.
>       h.. Electrical equipment used in the hospital must follow Hospital 
>Grades under Underwriter's Laboratory (UL) Standards 498 and 544. 
>Resistance measurement and leakage measurements can be determined using the 
>criteria in the National Fire Protection Association's Health Care 
>Facilities Handbook, Chapter 7.
>FIGURE VI:1-1. LASER CLASSIFICATIONS.
>
>
>
>
>       Class 1
>      The least-hazardous class. Considered incapable of providing damaging 
>levels of laser emissions.
>
>       Class 2
>      Applies only to visible laser emissions and may be viewed directly 
>for time periods of less than or equal to 0.25 seconds, which is the 
>aversion response time.
>
>       Class 3a
>      Dangerous under direct or reflected vision. These lasers are 
>restricted to the visible electromagnetic spectrum.
>
>       Class 3b
>      May extend across the whole electromagnetic spectrum and are 
>hazardous when viewed intrabeam.
>
>       Class 4
>      The highest-energy class of lasers, also extending across the 
>electromagnetic spectrum. This class of laser presents significant fire, 
>skin, and eye hazards.
>
>
>
>
>
>
>   a.. CONTROLS AND PREVENTION.
>     a.. ENGINEERING. All rooms should have adequate ventilation to remove 
>contaminants. If air recirculation is required, then adequate filtering 
>must be installed.
>     NOTE: Intensive care units (ICU's), particularly neonatal ICU's, may 
>be designed without walls between patient spaces. This may allow 
>aerosolized chemicals and x-ray radiation to escape to neighboring areas.
>
>     b..
>     c.. LOCAL VENTILATION.
>       a.. General Points.
>a. Hoods should be used for specific procedures, such as mixing 
>antineoplastic drugs. A scavenging system that contains a proper gas 
>disposal system must be in place and operable.
>
>b. Portable suction devices may be used for direct removal of contaminants. 
>Portable ventilation should be used for smoke plume removal during laser 
>surgery.
>
>c. Ethylene oxide should be ventilated through a nonrecycled or dedicated 
>ventilation system. For a discussion of ventilation of aeration units, 
>sterilizer door areas, sterilizer relief valves, and ventilation during 
>cylinder changes, see the appendix of 29 CFR 1910.1047 (Ethylene Oxide). 
>Alarms for inadequate ventilation and automatic shutdown should be in 
>place. Air pressure in laboratories and isolation rooms should be negative 
>so that contaminated air is drawn through the exhaust vents rather than 
>circulating throughout the rest of the building.
>
>d. Biological safety cabinets are primary containment devices used by 
>workers when handling moderate and high risk organisms. There are three 
>types of biological safety cabinets:
>
>   a.. Class I: Open fronted, negative pressure, ventilated cabinet.
>   b.. Class II: HEPA-filtered, recirculated air cabinet with an open front 
>face.
>   c.. Class III: A totally enclosed HEPA-filtered cabinet of gas-tight 
>construction.
>A class-III biological safety cabinet provides the highest protection to a 
>worker. The effectiveness of the biological safety cabinets is dependent on 
>air flow; therefore, the front intake grill and rear exhaust grill should 
>not be blocked.
>
>e. All windows must be covered or blacked out in laser surgical areas for 
>protection of employees outside the surgical area.
>
>f. Installation of automatic fire and explosion detection and protection 
>equipment is recommended. The type should be specific to the hazard in the 
>area.
>
>g. In the morgue, local vacuum systems should be in place for power saws. 
>Shields should be in place when significant splash hazards are anticipated.
>
>h. There should be a separate storage area for radioactive sources. This 
>area should be adequately shielded.
>
>i. Laser systems, especially ones with high voltage capacitance, should be 
>adequately covered. Also, bleeders and proper grounding should be attached 
>to the system. All operating room doors to rooms that house lasers should 
>contain safety interlocks, which shutdown the laser system if anyone enters 
>the room.
>
>j. Mixing of Methyl Methacrylate should be done in a closed system.
>
>k. Ultraviolet lamps have been used to prevent tuberculosis transmission.
>
>       a.. Administrative.
>       a. Workers should receive health and safety training.
>
>       b. Vaccination for rubella, measles, mumps, and influenza is 
>recommended, especially for women of child-bearing age.
>
>       c. Work-related stressors, such as inadequate work space, 
>unreasonable work load, lack of readily available resources, inadequate and 
>unsafe equipment, should be considered.
>
>       d. Appropriate emergency equipment (i.e., fire extinguishers, 
>showers, eye wash) should be readily available.
>
>       e. Perform periodic environmental sampling when indicated.
>
>       f. Replace hazardous substances with less hazardous substances 
>whenever possible (i.e., plastic for glass, small packets of chemicals, 
>pre-poured formalin containers). Provide appropriate containers for 
>disposal of sharps, hazardous waste, personal protective equipment.
>
>       g. Provide conveniently located and supplied hand washing 
>facilities.
>
>       h. Document and retain inventories of radioactive materials. Only 
>authorized personnel should have access to storage areas.
>
>       b.. Maintenance Schedules.
>       a. Hospital-grade electrical equipment including anesthesia 
>machines, portable x-ray machines and laser systems, biological safety 
>cabinets, and exhaust ventilation systems should have a preventive 
>maintenance schedule. Testing intervals of electric equipment shall be set 
>by the institution.
>
>       b. A specific person should have the responsibility for assuring 
>proper maintenance of the portable x-ray machines. Preventive and 
>corrective maintenance programs for x-ray machines are detailed in 21 CFR 
>1000, Radiological Health.
>
>       c. The anesthesia machine should be inspected and maintained at 
>least every four months. This should be done by factory service 
>representatives or other qualified personnel. Leakage of gas should be less 
>than 100 ml/min during normal operation.
>
>       d. The entire laser system should be properly maintained and 
>serviced according to the manufacturer's instructions. Only qualified 
>personnel from the manufacturer or in-house shall maintain the system. 
>Maintenance may only be done according to written standard operating 
>procedures.
>
>       e. A written log is recommended for any detected leak and any 
>service done on an ethylene oxide chamber. Sterilizer/aerator door gaskets, 
>valves, and fittings must be replaced when necessary.
>
>       c.. Training.
>       a. All hospital staff members should have training on electrical and 
>fire safety, hazard communication, and infection control by qualified 
>personnel. Some educators recommend hands on training with pre- and 
>post-tests.
>
>       b. In the hospital, specific training regarding hazardous substances 
>should be given. Only qualified personnel may handle the hazardous 
>substances or operate the specified machines.
>
>       d.. Warning Signs.
>a. Specific requirements regarding the warning signs to be used on 
>electrical equipment are outlined in UL No. 544. This should include a 
>Hospital Grade warning. Warning signs should be placed in areas where 
>exposure to ribavirin, antineoplastic agent spills, ethylene oxide, or 
>lasers is likely to occur.
>
>b. Contract employees should not endanger hospital employees and can be 
>controlled sometimes through use of privileges contracts.
>
>     a.. WORK PRACTICES.
>       1.. Hands should be washed frequently and thoroughly. Workers should 
>wash immediately after direct contact with any chemical, drug, blood, or 
>other body fluid.
>       2.. No eating, drinking, smoking or application of cosmetics should 
>take place in the lab.
>       3.. Needles and other sharp objects should be disposed of promptly 
>in impervious containers. Needles should not be clipped or recapped by 
>hand. See CPL 2-2.44B.
>       4.. There should be immediate and proper disposal of biohazardous 
>waste.
>       5.. Mouth pipetting is to be prohibited.
>       6.. Care should be taken not to create aerosols.
>       7.. Appropriate personal dosimetry devices should be worn when 
>working with radioactive materials.
>       8.. Electrical equipment that appears to be damaged or in poor 
>repair should not be used. Any shocks from electrical equipment should be 
>reported promptly to the maintenance department.
>       9.. Cylinders of compressed gases should be kept secured. They 
>should never be dropped or allowed to strike each other with force.
>       10.. Large pieces of broken glass should be removed with brooms and 
>disposed of in a separate container. Small pieces can be removed with 
>tongs. Glass should never be removed with fingers.
>       11.. Vaporizers of anesthesia machines should be turned off when not 
>in use. Also, proper face masks, sufficiently inflated endotracheal tubes, 
>and prevention of anesthetic spills will decrease the amount of waste 
>anesthetic gases in the operating room.
>       12.. Antineoplastic drug contact requires the use of an isotonic 
>wash to the body or eyes.
>     b.. PERSONAL PROTECTIVE EQUIPMENT.
>       1.. Lab coats should be worn in the laboratory area and removed 
>before leaving. Plastic or rubber aprons should be worn when there is a 
>potential for splashing.
>       2.. Gloves should be worn when performing tasks such as handling 
>hazardous chemicals, specimens, or hot materials. The type of glove should 
>be selected according to the task being performed, as follows:
>   a.. Latex or vinyl type gloves should be changed frequently and 
>inspected for punctures before putting them on.
>   b.. Double gloving to decrease the risk of exposure by penetration is 
>recommended if it does not interfere with the task.
>   c.. Less permeable surgical latex gloves are recommended over polyvinyl 
>gloves.
>   d.. Lead-lined gloves are to be worn in the direct x-ray field.
>       1.. Rubber-soled shoes should be worn to prevent slips and falls. 
>Rubber-lined shoe coverings may also be used to protect against spills or 
>dropped objects. Fluid-proof shoes must be worn if there is a possibility 
>of leakage to the skin.
>       2.. Protective eyewear or shields should be used if splashes of a 
>hazardous substance are likely to occur. Goggles that are tight-fitting may 
>prevent irritation of the eyes if aerosolized chemicals are present. 
>Goggles that protect the cornea, conjunctive and other ocular tissue are 
>required for all personnel in the operating room during laser surgery. The 
>wavelength of the laser output is the most important factor in determining 
>the type of eye protection to be used. Opaque goggles are to be worn if in 
>the direct x-ray field.
>       3.. Impervious or low permeability gowns should be worn when in 
>contact with antineoplastic drugs, ribavirin and blood/body fluids. These 
>gowns should be properly stored in the area of use if contaminated. Soiled 
>gowns should be washed or discarded. Lead-lined aprons are to be worn if in 
>the x-ray field.
>       4.. Respirators may be required in case of emergencies, such as 
>accidental spills and/or exposure to specific chemicals, e.g., formaldehyde 
>and ethylene oxide. Check for a respirator program.
>   a.. BIBLIOGRAPHY.
>American Hospital Association (AHA). 1966. Housekeeping Manual for Health 
>Care Facilities. AHA: Chicago.
>
>American National Standards Institute (ANSI). 1988. Standard for the Safe 
>Use of Lasers in Health Care Facilities. ANSI Z136.3-1988.
>
>American National Standards Institute (ANSI). 1982. Standard for Anesthetic 
>Equipment-Scavenging Systems for Excess Anesthetic Gases. ANSI Z79.11-1982.
>
>Chaff, L.F. 1989. Safety Guide for Healthcare Institutions. 4th ed. 
>American Hospital Publishing: Chicago.
>
>Charney, W. and Schirmer, J. 1990. Essentials of Modern Hospital Safety. 
>Lewis Publishers, Inc.: Chelsea, MI.
>
>ECRI. 1989. Ethylene Oxide: Protecting Your Employees. Hospital Hazardous 
>Management. Vol. 1, Nos. 1 & 2, Contact ECRI at 5200 Butler Pike, Plymouth 
>Meeting, PA 19462, (215) 825-6000.
>
>Hoeltge, G.A. 1986. Documentation of Safe Work Practices in the Clinical 
>Laboratory. Clinics in Laboratory Medicine 6(4):787-798.
>
>Joint Commission on the Accreditation of Hospitals. 1986. Accreditation 
>Manual for Hospitals. JCAH: Chicago.
>
>Miller, B.M. et al. 1986. Laboratory Safety Principles and Practices. 
>American Society for Microbiology: Washington D.C.
>
>National Council for Radiation Protection and Measurements (NCRP). 1978. 
>Radiation Protection for Medical and Allied Health Personnel. NCRP Report 
>#48. NCRP: Washington, DC.
>
>National Fire Protection Association (NFPA). 1987. Health Care Facilities 
>Handbook. 2nd ed. NFPA: Quincy, MA.
>
>National Institute for Occupational Safety and Health (NIOSH). 1977. 
>Criteria for a Recommended Standard: Occupational Exposure to Waste 
>Anesthetic Gases and Vapors. DHEW: NIOSH Publication No. 77-140. NIOSH: 
>Cincinnati, OH.
>
>National Institute for Occupational Safety and Health (NIOSH). 1988. 
>Guidelines for Protecting the Safety and Health of Health Care Workers. 
>DHHS: NIOSH Publication No. 88-119. NIOSH: Cincinnati, OH.
>
>National Institute for Occupational Safety and Health (NIOSH). 1989. 
>Ethylene Oxide Sterilizers in Health Care Facilities: Engineering Controls 
>and Work Practices. DHHS: NIOSH Publication No. 89-116. July 13, 1989. 
>NIOSH: Cincinnati, OH.
>
>Occupational Safety and Health Administration (OSHA). 1987. Chemical 
>Information Manual. U.S. Government Printing Office: Washington, DC.
>
>Occupational Safety and Health Administration (OSHA). 1989. Enforcement 
>Procedures for Occupational Exposure to Hepatitis B Virus (HBV) and Human 
>Immunodeficiency Virus (HIV). OSHA: Washington, DC.
>
>Occupational Safety and Health Administration (OSHA). 1986. Guidelines for 
>Antineoplastic (Cytotoxic) Drugs. OSHA: Washington, DC.
>
>Patterson, W. et al. 1985. Occupational Hazards to Hospital Personnel. 
>Annals of Internal Medicine. 102:658-680.
>
>Richmond, J. 1988. Safe Practices and Procedures for Working with Human 
>Specimens in Biomedical Research Laboratories. Journal of Clinical 
>Immunoassay 11(3): 115-119.
>
>Rose, S.L. 1984. Clinical Laboratory Safety. J.B. Lippincott Co.: 
>Philadelphia, PA.
>
>Sommargren, C.E. (ed.). 1989. AACN Handbook on Occupational Hazards for the 
>Critical Care Nurse. American Association of Critical-Care Nurses, 
>Occupational Hazards Task Force. AACN: Chicago, IL.
>
>Texas Hospital Association (THA) and Shared Hospital Electrical Safety 
>Services. 1973. Electrical Safety Guide. THA: Austin.
>
>United States Department of Health and Human Services. 1988. Biosafety in 
>Microbiological and Biomedical Laboratories. HHS: Washington, DC.
>
>Vesley, D., Hartman, M.S., and Heidi, M. 1988. Laboratory Acquired 
>Infections and Injuries in Clinical Laboratories: A 1986 Survey. American 
>Journal of Public Health 78(9):1213-1215.
>
>
>
>APPENDIX VI:1-1. BIOLOGICAL AGENTS--BLOOD AND BODY FLUIDS.
>
>       Use or exposure
>
>       Contact with blood and body fluids may occur as a result of medical 
>and surgical procedures, such as labor and delivery, blood or body fluid 
>collection and analysis, the handling of contaminated waste (e.g., gloves, 
>linens, bandages, protective clothing, etc.) or the suctioning of airways. 
>Exposure usually occurs because inadequate infection control procedures are 
>in use.
>        Health effects
>
>       Acute: The severity of infection depends on:
>
>         a.. The number of pathogens encountered;
>         b.. The worker's resistance, which is affected by such things as: 
>state of health, predisposing diseases, age, sex, and hereditary factors;
>         c.. Portal of entry (via inhalation, ingestion, mucous membrane or 
>skin contact, or direct inoculation); and
>         d.. Virulence of the organism.
>       Chronic: Reproductive consequences ranging from congenital anomalies 
>to death of the fetus and other chronic diseases, such as cirrhosis of the 
>liver and primary liver cancer, may result from some viruses including 
>hepatitis B, rubella, cytomegalovirus, herpes, and human immunodeficiency 
>virus (HIV).
>
>       Biological agents--Refer to OSHA Instruction CPL 2-2.44B: 
>Enforcement Procedures for Occupational Exposure to Hepatitis B Virus (HBV) 
>and Human Immunodeficiency Virus (HIV).
>
>
>
>
>
>APPENDIX VI:1-2. CHEMICAL AGENTS.
>
>The following are specifically mentioned because of the severity of their 
>health effects. This list is by no means all-inclusive.
>
>       Use or exposure
>
>       Ethylene oxide (EtO)
>
>       A disinfectant and sterilant, it is usually used in the central 
>supply area. Exposure usually occurs from improper aeration of the ethylene 
>oxide chamber after the sterilizing process. It can also occur in 
>outpatient surgery clinics and in the cardiac catheterization laboratory 
>(29 CFR 1910.1047).
>        Health effects
>
>       Acute: Respiratory and eye irritation, vomiting, and diarrhea.
>
>       Chronic: Altered behavior, anemia, secondary respiratory infections, 
>skin sensitization, miscarriages, and reproductive problems. Carcinogen.
>
>       Waste anesthetic gases such as nitrous oxide, Halothane, Enfluorane
>
>       Waste gases result from poor work practices during the 
>anesthetization of patients, improper or inadequate maintenance of the 
>machine, and/or patient exhalation after the surgical procedure (recovery).
>        Acute: Drowsiness, irritability, depression, headaches, nausea, and 
>problems with coordination and judgement.
>
>       Chronic: Embryotoxicity, liver and kidney disease, and cancer.
>
>
>       Antineoplastic (cancer) drugs, such as Vincristine, Dacarbazine, 
>Mitomycin, Cytosine Arabinoside, and Fluorouracil
>
>
>       Antineoplastic drugs, used in the treatment of cancer and other 
>tumors, are usually given as intravenous fluids. Mixing usually occurs in 
>the pharmacy area of the hospital in a biological safety cabinet. Exposure 
>may occur during preparation, administration or disposal of the drug and 
>equipment.
>        Acute: Severe soft-tissue damage, fetotoxicity, headaches, 
>lightheadedness, dizziness, and nausea.
>
>       Chronic: Chromosomal damage, teratogenesis, and carcinogenesis.
>
>
>       Methyl methacrylate (MMA)
>
>       An acrylic cement-like substance used to secure prostheses to bone 
>during orthopedic surgery. Exposure usually occurs during mixing, 
>preparation, and in the operating room.
>        Acute: Eye, skin and mucous membrane irritant. Acute effects have 
>varied from a decrease in blood pressure to (rarely) cardiac arrest.
>
>       Chronic: Degeneration of the liver, mutagenesis, and teratogenesis.
>
>
>
>
>
>       Ribavirin
>
>       An antiviral drug used to treat some infants and young children with 
>lower respiratory syncytial virus (RSV) infections. This drug is 
>aerosolized to a respirable size of approximately 1.3 microns and is 
>usually administered to the patient in an oxygen tent or face mask. This is 
>when exposure can occur.
>        Acute: Headaches, coughing, dry upper respiratory tract and 
>dry-burning eyes.
>
>       Chronic: Carcinogenesis, fertility impairment and fetotoxicity.
>
>
>       Formaldehyde
>
>       Used as a fixative and is commonly found in most laboratories and 
>the morgue (29 CFR 1910.1048).
>        Acute: Eye and respiratory irritation from the liquid and vapor 
>forms. Severe abdominal pains, nausea, vomiting and possible loss of 
>consciousness could occur, if ingested in large amounts.
>
>       Chronic: High concentration of vapor inhaled for long periods can 
>cause laryngitis, bronchitis or bronchial pneumonia. Prolonged exposure may 
>cause conjunctivitis. Nasal tumors have been reported in animals. Suspected 
>carcinogen.
>
>
>       Toluene or Xylene
>
>
>       Solvents used to fix tissue specimens and rinse stains. They are 
>primarily found in the histology, hematology, microbiology, and cytology 
>laboratories (29 CFR 1910.1000 Subpart Z).
>        Acute: Eye and mucous membrane irritation from vapor and liquid 
>forms. Dizziness, headache, and mental confusion from inhalation of vapor. 
>Ingestion or absorption through the skin can cause poisoning. There is a 
>potential for thermal burns as it is extremely flammable.
>
>       Chronic: If the xylene or toluene contains benzene as an impurity, 
>repeated breathing of the vapor over long periods may cause leukemia. 
>Prolonged skin contact may cause dermatitis. Tolune has been implicated in 
>reproductive disorders.
>
>       Acrylamide
>
>       The resin, usually found in research labs, is used to make gels for 
>biochemical separations (29 CFR 1910.1000 Subpart Z).
>        Acute: Eye and skin irritation.
>
>       Chronic: Central nervous system disorders, i.e., polyneuropathy. 
>Suspected carcinogen. Mutagen.
>
>
>
>
>APPENDIX VI:1-3. PHYSICAL AGENTS.
>
>       Use or exposure
>        Health
>
>       effects
>
>       Laser
>
>       Used in the operating rooms for excision and cauterization of 
>tissue. Class 3b and 4 lasers are most often used. Exposure usually occurs 
>from unintentional operation and/or when proper controls are not in effect. 
>The high electrical energy used to generate the beam is a potential shock 
>hazard. The smoke plume during a surgical procedure and the laser's 
>reaction to certain explosive or flammable agents also present hazards in 
>the operating room.
>        Acute: From direct beam exposure, burns to skin and eyes possibly 
>resulting in blindness. Chemical by-products in the smoke plume may cause 
>irritation to the eyes, nose and throat, and nausea (see OSHA Hazard 
>Information Bulletins). Biological and inert particulates can also be found 
>in the smoke plume but these have not been well studied for their effects.
>
>       Chronic: Unknown.
>
>       Ionizing radiation
>
>       Portable and fixed X-ray machines are used for diagnostic 
>procedures. Exposure occurs when unprotected employees are near a machine 
>in operation. The degree of exposure depends on the amount of radiation, 
>the duration of exposure, the distance from the source and the type of 
>shielding in place.
>
>       Kits containing radioactive isotopes or specimens and excreta of 
>humans and animals who have received radionucleotides may pose a hazard. 
>Exposure may also result from handling of radioactive spills (29 CFR 
>1910.1096).
>        Effects of radiation exposure are somatic (body) and/or genetic 
>(offspring) in nature.
>
>       Acute: Erythema and dermatitis. Large whole-body exposures cause 
>nausea, vomiting, diarrhea, weakness, and death.
>
>       Chronic: Skin cancer and bone marrow suppression. Genetic effects 
>may lead to congenital defects in the employee's offspring.
>
>
>       Magnetic radiation
>
>
>       Magnetic resonance instrumentation.
>        No conclusive effects are documented.
>
>
>       Electrical hazards
>
>
>       Exposure may occur when there is lack of maintenance to any 
>electrical equipment, abuse, and lack of understanding of the equipment 
>and/or its controls. Oxygen-enriched atmospheres and water may contribute 
>to hazardous conditions.
>        Acute: Painful shocks, respiratory inhibition, deep burns (electric 
>and thermal) heart rate irregularities, death.
>
>       Chronic: No documented effects.
>
>
>       Ultraviolet radiation
>
>
>       Ultraviolet lamps are sometimes used in biological safety cabinets.
>        Acute: Skin burns, damage to the eye.
>
>       Chronic: No documented effects other than cataracts.
>
>
>       Compressed gases
>
>
>       Compressed gases are used in many clinical laboratories. They are 
>found in varying sizes and in pure or mixed states. Examples: ammonia, 
>carbon dioxide, and nitrogen.
>        Compressed gases can be toxic, radioactive, flammable, and 
>explosive. These effects arise from the compression of the gas and the 
>health effects of the chemical itself.
>
>
>       Glass
>
>
>       Glassware is used as bottles, beakers, flasks, test tubes, pipettes, 
>and tubing. Chipped, cracked, badly etched glassware and sharp edges 
>present hazards, as does broken glass.
>
>       Cuts, scratches, abrasions, are potential locations for infection.
>
>
>
>
>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
>DANA MITRA LINGKUNGAN {Friends of the Environment Fund}
>Pusat Niaga Duta Mas Fatmawati, Blok B1/12
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