Frederik and lists,

Thank you for the clear answers. I am enjoying NP and am impressed by its scholarship. I think there is still one issue that is most important for biosemiotics.

At 06:48 PM 12/26/2014, Frederik wrote:

Linear discrete storage is of paramount importance but still only one side of the coin - the other being spatial information, e.g. in visual, continuous icons. One of the early important papers in biosemiotics (by Hoffmeyer and Emmeche, in Semiotica, around 1990) made the point that information inheritance in biology is double. One part is the discrete information in the genes - the other the continuous information incarnated in the structure of the cell.

HP: The empirical issue is: How important for evolution are continuous dynamic icons? Of course evolution has discovered all kinds of epigenetic inheritance effects.This has been a hot topic since Lamarck. Today there is even a Journal, <http://www.degruyter.com/view/j/ngi>Non-Genetic Inheritance, (only one issue per year!). A critical review of "soft inheritance" is in <http://rspb.royalsocietypublishing.org/content/279/1740/2913>Proc.<http://rspb.royalsocietypublishing.org/content/279/1740/2913>Roy.<http://rspb.royalsocietypublishing.org/content/279/1740/2913>Soc.<http://rspb.royalsocietypublishing.org/content/279/1740/2913>B 6/28/2012 by Dickins and Rahman.

FS: So here I (with Hoffmeyer and Emmeche) disagree with Howard: the egg cell itself forms part of the inherited information (in gendered organisms) - in simpler organisms, the cell structure is inherited by the simple duplication of it.

HP: What structures making up an egg are not under genetic control? Clearly the atoms, C, N, O, H, etc. are not. They are fixed parts of any gene-controlled molecule. But when a cell divides do you want to say carbon atoms in the new cells are inherited?

In any case, this is not the fundamental biosemiotic issue. From the physicist's point of view (e.g., Boltzman, Schrödinger, von Neumann, Wigner, et al) life is a fundamental problem because it increases or maintains intricate, non-statistical structured order in a very noisy universe -- noise which causes all other ordered structures to eventually dissipate, or dissipate faster than life (eventually, nothing escapes dissipation).

The first level answer was grasped by Darwin. There must be a heritable memory that maintains structures (growth and metabolism). But this answer still has the noise problem. Why is the memory reliable? The second level answer should be a biosemiotic principle. It is supported by all kinds of evidence: The only sufficiently reliable evolvable memories are discrete linear symbol systems. That is not the only condition. To be evolvable in an open-ended sense, the symbol system must form a language with unlimited expressive power (e.g., <https://www.academia.edu/2081540/The_physical_basis_of_coding_and_reliability_in_biological_evolution>Pattee<https://www.academia.edu/2081540/The_physical_basis_of_coding_and_reliability_in_biological_evolution>, 1968 to <https://www.academia.edu/3144895/The_Necessity_of_Biosemiotics_Matter-Symbol_Complementarity>2007). Hoffmeyer and Emmeche have a point, but the <http://en.wikipedia.org/wiki/RNA_world_hypothesis>RNA Model now appears as a good origin possibility.

One more question. I can see that the Peircean triad of symbol, index, icon makes sense for weathercocks, but I need examples of how it could add to the current (parsimonious) description of genetic expression in single cells. What are the index and icon vehicles?

Howard
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