At the Department of Computer Science at the VU University Amsterdam, a PhD 
position for four years is available on a research project devoted to

  Engineering Executable Models of Biological Networks


The project
-----------

The goal of the project is to describe gene regulatory networks by formal 
interaction patterns/models. Using these formal models, we aim to derive new 
insights in the behaviour of gene networks. These models, ultimately, describe 
cells' behaviour, and cell components, as independent, communicating entities. 
Simulating cell behaviour this way at the same time promises new insights and 
poses new challenges on the execution and verification environment due to the 
complexity, heterogeneity and variability of the modeled entities.

The work will start with the application of our formal framework using Petri 
nets to model gene network behaviour. Additionally, extensions of the framework 
and new methods and tools for analysis of the behaviour patterns will be 
developed.

For more detailed information on the project, see

  http://www.few.vu.nl/~feenstra/projects/bioexe.pdf


Research groups
---------------

This project is a collaboration between two research groups at the VU: 
Bioinformatics (Anton Feenstra and Jaap Heringa) and Theoretical Computer 
Science (Wan Fokkink). For experimental validation of predictions, we 
collaborate with two experimental groups; the group Receptor Systems Biology at 
the VU (Martine Smit), and Bertie Göttgens at
the Cambridge Institute for Medical Research.

For more information on the involved research groups, see

  http://www.cs.vu.nl/en/sec/cs/
  http://www.ibi.vu.nl/
  http://www.cs.vu.nl/~tcs


Qualifications
--------------

Candidates should have completed their studies in computer science, 
bioinformatics or a closely related area. Experience with biological systems, a 
good theoretical background, and an open attitude to applications are 
considered advantages. You should enjoy working in an internationally oriented 
and interdisciplinary research environment. Communicative skills and the 
ability to work in a team are important.


Information and application
---------------------------

For further information about these positions please contact either:

  Dr. Anton Feenstra     [email protected]  tel. +31 (0)20 5987783
  Prof.dr. Wan Fokkink   [email protected]   tel. +31 (0)20 5987735
  Prof.dr. Jaap Heringa  [email protected]     tel. +31 (0)20 5987649

You are invited to send an application by email to the above email addresses no 
later than September 1, 2012. Your application should consist of a cover 
letter, a curriculum vitae (including detailed information regarding your 
academic degree), and the names and addresses of two references.
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