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New Message on Pituitary Chat

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From: PTResearcher2
Message 3 in Discussion

Hi there,   I am so sorry for the loss of your pregnancy. Ovarian cysts can be 
caused by pit tumors and the hormonal imbalance that they cause. I once had an 
8cm (complex) cystic tumor on my right ovary. I have constant ovarian cysts 
that constantly burst (pain.) I had a diagnostic lap in 2006 and I had large 
cysts on both ovaries with no explanation (they were looking for 
endometreosis.) I continue to have rep problems (fibroids and PCOS as well) and 
I believe that they are all due to the pit tumor and the hormonal imbalance 
that it causes. I do not have Acromegaly, however. I have MEN I (Multiple 
Endocrine Neoplasia type I) and cyclical pituitary Cushing's disease. I have 
had a known pit tumor for 11 years (with symptoms.) My rep problems started 11 
years ago-I don't think that is a coincidence.    I believe that any tumor or 
cyst on the pit gland can mess up our hormones and hormonal balance. Gonadal 
hormones are very sensitive. Have you had your LH:FSH checked? Also your 
testosterone and DHEA-S?   Do you see a reproductive endo? If not, I would 
advise that you see one. They know more about hormones, specifically the 
gonadal hormones, than the average ob/gyn.   Have you been treated for the 
Acromegaly?    Some info on general ovarian cysts:   
http://www.emedicine.com/med/topic1699.htm   Info on IGF-1 and ovarian cysts:   
http://www.emedicine.com/med/topic2173.htm A proposed mechanism for anovulation 
and elevated androgen levels suggests that, under the increased stimulatory 
effect of luteinizing hormone (LH) secreted by the anterior pituitary, 
stimulation of the ovarian theca cells is increased. In turn, these cells 
increase the production of androgens (eg, testosterone, androstenedione). 
Because of a decreased level of follicle-stimulating hormone (FSH) relative to 
LH, the ovarian granulosa cells cannot aromatize the androgens to estrogens, 
and this inability leads to decreased estrogen levels and consequent 
anovulation. Growth hormone (GH) and insulin-like growth factor-1 (IGF-1) may 
also augmenting effect on ovarian function.     A serum IGF-1 level should be 
checked to rule out acromegaly. Serum IGF-1 is a sensitive and specific marker 
of GH excess. Normal levels rule out GH excess. 
  
Take care.   Meri

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