Hi Danilo, We have done some work looking at classifiers trained on one sensory modality and tested on another modality (using pymvpa) to find sensory-independent representations, for example:
http://www.jneurosci.org/content/32/47/16629.abstract In that paper the classification was done within individuals, but we have done it successfully across individuals as well (leave one subject out cross-validation). There are many reasons why an analysis such as the one you propose might fail, but if learning transfers from one study to the other I think that is very interesting. I would be interested to hear other opinions on this. -Jonas ---- Jonas Kaplan, Ph.D. Research Assistant Professor Brain & Creativity Institute University of Southern California On Mar 14, 2013, at 11:42 AM, Danilo Bzdok <[email protected]> wrote: > Dear list, > > I would like to apply pattern classification to a single seed region, in > which two fMRI studies revealed convergence. Each of these fMRI studies used > the same stimulus material across four tasks (to focus on top-down effects by > subtraction). Both these fMRI studies used the same four tasks, but differed > in the sensory modality on which the task is based (visual vs auditory). In > every other respect the fMRI settings/protocoll were practically identical. > Here's now my question: Is it possible to train a classifier for neural > activity patterns in the converging seed region to test whether activity in > that area is sensory-independent or sensory-specific? Or is there too much > confound when comparing between two subjects from very similar yet different > fMRI studies? Any help would be greatly appreciated. > > -- > Best, > Danilo Bzdok > _______________________________________________ > Pkg-ExpPsy-PyMVPA mailing list > [email protected] > http://lists.alioth.debian.org/cgi-bin/mailman/listinfo/pkg-exppsy-pymvpa _______________________________________________ Pkg-ExpPsy-PyMVPA mailing list [email protected] http://lists.alioth.debian.org/cgi-bin/mailman/listinfo/pkg-exppsy-pymvpa

