Reading. Crosswords. Jeopardy. Interesting friends. Same for sexual
response- use it or lose it- muscles and nerve bundles. Yet, some
athletic types seem to fall apart as they have stressed out their
joints- Jane Fonda with two hip-replacements, for instance

On Dec 8, 4:55�am, Liberal mike 532 <[EMAIL PROTECTED]> wrote:
> i think the brain is like a muscle that needs to be worked in order to
> keep it functioning .
>
> On Dec 8, 5:51�am, rigsy03 <[EMAIL PROTECTED]> wrote:
>
>
>
> > I think Alzheimer's is heriditary and depends on good genes and a
> > sparkling curious mind. My mind sparkles so frequently I have to calm
> > it down with American whiskey! :-)
>
> > On Dec 8, 4:46 am, Liberal mike 532 <[EMAIL PROTECTED]> wrote:
>
> > > Attacking Alzheimer's with Red Wine and 
> > > Marijuanahttp://www.alternet.org/drugreporter/110806/
> > > Two new studies point to a wonderful way to ward off Alzheimer's
> > > disease and other forms of age-related memory loss. This article
> > > first
> > > appeared on Miller-McCune.com.
>
> > > Two new studies suggest that substances usually associated with
> > > dulling the mind -- marijuana and red wine -- may help ward off
> > > Alzheimer's disease and other forms of age-related memory loss. Their
> > > addition comes as another study dethrones folk remedy ginkgo biloba
> > > as
> > > proof against the disease.
>
> > > At a November meeting of the Society of Neuroscience in Washington,
> > > D.C., researchers from Ohio State University reported that THC, the
> > > main psychoactive substance in the cannabis plant, may reduce
> > > inflammation in the brain and even stimulate the formation of new
> > > brain cells.
>
> > > Meanwhile, in the Nov. 21 issue of the Journal of Biological
> > > Chemistry, neurologist David Teplow of the University of California,
> > > Los Angeles reported that polyphenols -- naturally occurring
> > > components of red wine -- block the formation of proteins that build
> > > the toxic plaques thought to destroy brain cells. In addition, these
> > > substances can reduce the toxicity of existing plaques, thus reducing
> > > cognitive deterioration.
>
> > > Together, the studies suggest scientists are gaining a clearer
> > > understanding of the mechanics of memory deterioration and
> > > discovering
> > > some promising approaches to prevention.
>
> > > Previous research has suggested that polyphenols -- which are found
> > > in
> > > high concentrations in tea, nuts and berries, as well as cabernets
> > > and
> > > merlots -- may inhibit or prevent the buildup of toxic fibers in the
> > > brain. These fibers, which are primarily composed of two specific
> > > proteins, form the plaques that have long been associated with
> > > Alzheimer's disease.
>
> > > UCLA's Teplow and his colleagues monitored how these proteins folded
> > > up and stuck to each other to produce aggregates that killed nerve
> > > cells in mice. They then treated the proteins with a polyphenol
> > > compound extracted from grape seeds. They discovered the polyphenols
> > > blocked the formation of the toxic aggregates.
>
> > > "What we found is pretty straightforward," Teplow declared. "If the
> > > amyloid beta proteins can't assemble, toxic aggregates can't form,
> > > and, thus, there is no toxicity." If this also proves true in human
> > > brains, it means administration of the compound to Alzheimer's
> > > patients could "prevent disease development and also ameliorate
> > > existing disease," he said. Human clinical trials are upcoming.
>
> > > At Ohio State, researchers led by psychologist Gary Wenk are studying
> > > the protective effects of tetrahydrocannabinol, commonly known as
> > > THC.
> > > They found that administering a THC-like synthetic drug to older rats
> > > performed better at a memory test than a control group of non-
> > > medicated elderly rodents.
>
> > > In some of the rats, the drug apparently lowered inflammation in the
> > > hippocampus -- the region of the brain responsible for short-term
> > > memory. It also seems to have stimulated the generation of new brain
> > > cells.
>
> > > "When we're young, we reproduce neurons and our memory works fine,"
> > > said co-author Yannick Marchalant, another Ohio State psychologist.
> > > "When we age, the process slows down, so we have a decrease in new
> > > cell formation in normal aging. You need those cells to come back and
> > > help form new memories, and we found that this THC-like agent can
> > > influence creation of those cells."
>
> > > Wenk added two cautionary notes to his report. First, to be
> > > effective,
> > > any such treatment along these lines would have to take place before
> > > memory loss is obvious. Second, the researchers still have much work
> > > to do.
>
> > > "We need to find exactly which receptors are most crucial" to the
> > > generation of new brain cells, he said. This discovery would "ideally
> > > lead to the development of drugs that specifically activate those
> > > receptors."
>
> > > In the meantime, should aging baby boomers who are worried about old-
> > > age mental impairment light up a joint? Wenk was cautious in his
> > > answer, no doubt because marijuana is suspected to be harmful to
> > > health in other ways.
>
> > > "Could people smoke marijuana to prevent Alzheimer's disease if the
> > > disease is in the family? We're not saying that, but it might
> > > actually
> > > work," he said. "What we are saying is it appears that a safe, legal
> > > substance the mimics those important properties of marijuana can work
> > > on receptors in the brain to prevent memory impairments in aging. So
> > > that's really hopeful."- Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
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