The abnormal genes and DNA sequences underlying most inherited genetic
diseases in jews have been identified. This progress has helped to
understand the nature of these diseases, to increase the prospects for
treatment, to facilitate genetic counseling, and to elucidate the
population genetics underlying the segregation of these diseases in jewish
communities.
Genetic diseases with a high prevalence in Jews are mostly recessive. In
general, over 1,000 recessive diseases have been discovered. Most are rare
but the prevalence of some of these diseases is increased 100-fold or more
in jewish as in other isolated ethnic groups with predominant inbreeding.
This increased prevalence is usually but not invariably confined to
individual Jewish ethnic groups ("*edot* Israel") and not found in Jews in
general. Most are severe and often lead to early death. In some diseases
genetic analysis has identified the first appearance of an abnormal
"founder" gene originating in a small number of individuals within a Jewish
group. This creates a genetic bottleneck whereby the prevalence of a
recessive genetic disease is maintained at a high level by subsequent
inbreeding.
Ashkenazim are a relatively homogeneous group despite their settlement in
different European countries for centuries. The high prevalence of some 20
"Ashkenazi diseases" in this group dates from founder effects and
bottlenecks in the era after 75 C.E. and between 1100 and 1400C.E. The most
common of these diseases are the neurodegenerative Tay-Sachs disease and
Gaucher type I disease, which has more widespread clinical features. These
"lysosomal storage" diseases result from enzyme deficiencies. Familial
dysautonomia affects peripheral nerves and predominantly affects certain
Ashkenazi groups. The carrier rate in Ashkenazim in Israel of Polish
descent is 1 in 18 compared with 1 in 99 in those of non-Polish descent.
Ashkenazi women with a family history of breast cancer are at increased
risk of developing this disease, especially of early onset, due to the high
(2.5%) prevalence of BRCA1 and BRCA2 gene mutations in this population.
They also have a high incidence of ovarian cancer of which a large
percentage, estimated at up to 41%, are attributable to "founder" mutations
in these genes. Approximately 1 in 25 Ashkenazim are carriers for one of
these disorders, resulting in the birth of one affected child in
approximately every 3,000 Ashkenazi live births for each condition.
Screening is essential at least in those with a family history. The gene
mutations responsible for other less common diseases with a high prevalence
in the Ashkenazi population have also been identified allowing accurate
diagnosis in at risk families. Prevention programs have already reduced the
number of affected children born to these families by over 90%.
Sephardi Jews are genetically much more heterogeneous than ashkenazi jews
and genetic diseases in high prevalence in Sephardi communities reflect
their country of origin such as Iraq, Yemen, and Morocco. Some genetic
disorders characteristic of the Mediterranean region are relatively common
in all Sephardi and in non-Jewish communities, marking constant migration.
Genetic screening for the abnormal hemoglobin responsible for thalassemia
is well established. Familial Mediterranean fever (FMF) is an intermittent
febrile illness, often difficult to diagnose. Five variants of abnormal
sequence have been detected in the defective gene associated with FMF which
give important insights into disease severity and its occurrence in
different communities.
On Friday, June 28, 2013 12:47:38 PM UTC-5, Travis wrote:
>
>
>
>
>
> http://www.wvwnews.net/story.php?id=9914****
>
> *Muslim Inbreeding* Report; Posted on: 2011-03-16 19:50:48 ****
>
>
>
>
> Nicolai Sennels is a Danish psychologist who has done extensive research
> into a little-known problem in the Muslim world: the disastrous results of
> Muslim inbreeding brought about by the marriage of first-cousins.
>
> This practice, which has been prohibited in the Judeo-Christian tradition
> since the days of Moses, was sanctioned by Muhammad and has been going on
> now for 50 generations (1,400 years) in the Muslim world.
>
> This practice of inbreeding will never go away in the Muslim world, since
> Muhammad is the ultimate example and authority on all matters, including
> marriage.
>
> The massive inbreeding in Muslim culture may well have done virtually
> irreversible damage to the Muslim gene pool, including extensive damage to
> its intelligence, sanity, and health.
>
> According to Sennels, close to half of all Muslims in the world are inbred.
> In Pakistan , the numbers approach 70%. Even in England , more than half of
> Pakistani immigrants are married to their first cousins, and in Denmark the
> number of inbred Pakistani immigrants is around 40%.
>
> The numbers are equally devastating in other important Muslim countries:
> 67%
> in Saudi Arabia , 64% in Jordan , and Kuwait , 63% in Sudan , 60% in Iraq ,
> and 54% in the United Arab Emirates and Qatar .
>
> According to the BBC, this Pakistani, Muslim-inspired inbreeding is thought
> to explain the probability that a British Pakistani family is more than 13
> times as likely to have children with recessive genetic disorders. While
> Pakistanis are responsible for 3% of the births in the UK , they account
> for
> 33% of children with genetic birth defects.
>
> The risk of what are called autosomal recessive disorders such as cystic
> fibrosis and spinal muscular atrophy is 18 times higher and the risk of
> death due to malformations is 10 times higher. Other negative consequences
> of inbreeding include a 100% increase in the risk of stillbirths and a 50%
> increase in the possibility that a child will die during labor.
>
> Lowered intellectual capacity is another devastating consequence of Muslim
> marriage patterns. According to Sennels, research shows that children of
> consanguineous marriages lose 10-16 points off their IQ and that social
> abilities develop much slower in inbred babies. The risk of having an IQ
> lower than 70, the official demarcation for being classified as "retarded,"
> increases by an astonishing 400% among children of cousin marriages.
> (Similar effects were seen in the Pharaonic dynasties in ancient Egypt and
> in the British royal family, where inbreeding was the norm for a
> significant
> period of time.)
>
> In Denmark , non-Western immigrants are more than 300% more likely to fail
> the intelligence test required for entrance into the Danish army.
>
> Sennels says that "the ability to enjoy and produce knowledge and abstract
> thinking is simply lower in the Islamic world." He points out that the Arab
> world translates just 330 books every year, about 20% of what Greece alone
> does.
>
> In the last 1,200 years of Islam, just 100,000 books have been translated
> into Arabic, about what Spain does in a single year. Seven out of 10 Turks
> have never even read a book.
>
> Sennels points out the difficulties this creates for Muslims seeking to
> succeed in the West. "A lower IQ, together with a religion that denounces
> critical thinking, surely makes it harder for many Muslims to have success
> in our high-tech knowledge societies."
>
> Only nine Muslims have every won the Nobel Prize, and five of those were
> for
> the "Peace Prize." According to Nature magazine, Muslim countries produce
> just 10% of the world average when it comes to scientific research
> (measured
> by articles per million inhabitants).
>
> In Denmark , Sennels' native country, Muslim children are grossly
> over-represented among children with special needs. One-third of the budget
> for Danish schools is consumed by special education, and anywhere from 51%
> to 70% of retarded children with physical
> handicaps in Copenhagen have an immigrant background.
>
> Learning ability is severely affected as well. Studies indicated that 64%
> of
> school children with Arabic parents are still illiterate after 10 years in
> the Danish school system. The immigrant drop-out rate in Danish high
> schools
> is twice that of the native-born.
>
> Mental illness is also a product. The closer the blood relative, the higher
> the risk of schizophrenic illness. The increased risk of insanity may
> explain why more than 40% of the patients in Denmark 's biggest ward for
> clinically insane criminals have an immigrant background.
>
> The U.S. is not immune. According to Sennels, "One study based on 300,000
> Americans shows that the majority of Muslims in the USA have a lower
> income,
> are less educated, and have worse jobs than the population as a whole."
>
> Sennels concludes:
> There is no doubt that the wide spread tradition of first cousin marriages
> among Muslims has harmed the gene pool among Muslims. Because Muslims'
> religious beliefs prohibit marrying non-Muslims and thus prevents them from
> adding fresh genetic material to their population, the genetic damage done
> to their gene pool since their prophet allowed first cousin marriages 1,400
> years ago are most likely massive. (This has produced) overwhelming direct
> and indirect human and societal consequences.
>
> Bottom line: Islam is not simply a benign and morally equivalent
> alternative
> to the Judeo-Christian tradition. As Sennels points out, the first and
> biggest victims of Islam are Muslims. Simple Christian compassion for
> Muslims and a common-sense desire to protect Western civilization from the
> ravages of Islam dictate a vigorous opposition to the spread of this dark
> and dangerous religion. These stark realities must be taken into account
> when we establish public policies dealing with immigration from Muslim
> countries and the building of mosques in the U.S.
>
>
> ****
>
>
> __
>
>
>
>
>
>
> __,_._,___
>
>
>
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