I found this by chance while looking for something else. I don't know if it's worth the effort to commit this, or if a revision bump is needed.
Thanks. Index: Makefile =================================================================== RCS file: /cvs/ports/devel/py-esptool/Makefile,v retrieving revision 1.5 diff -u -p -r1.5 Makefile --- Makefile 2 Nov 2021 00:00:48 -0000 1.5 +++ Makefile 21 Nov 2021 17:55:25 -0000 @@ -20,7 +20,7 @@ MODPY_SETUPTOOLS = Yes RUN_DEPENDS += devel/py-serial${MODPY_FLAVOR} \ security/py-aes${MODPY_FLAVOR} \ - security/py-ecdsa${MODPY_FLAVOR} \ + security/py-ecdsa${MODPY_FLAVOR} FLAVORS = python3 FLAVOR = python3