Penelitian begini biasanya dibikin oleh orang-orang kafir dan
bukan oleh orang-orang Islam tipikal yang memang dungu-dugnu
kayak babi....
Orang Isam tikpikal itu lebih senang berbunuhan kayak di Iraq,
di Pakistan, atau di Darfur
Atau biking teror kayak di New York, Bali, Jakarta, London,
Madrid dll.
BBC NEWS
Parkinson's 'targets cell boiler'
Parkinson's disease may trigger symptoms by crippling the key energy-
producing "boiler room" of brain cells, research suggests.
Two studies by US and Korean scientists focused on a mutant protein
implicated in inherited Parkinson's.
In tests on fruit flies, they found it disabled energy-producing cell
structures called mitochondria, damaging cells controlling movement.
The research is published online by the journal Nature.
The identification and study of such Parkinson's disease-
causing genes can be of great value in understanding the disease
processes Kieran Breen
Previous research has established that an inherited form of early-
onset Parkinson's - autosomal recessive juvenile parkinsonism (AR- JP)
- is caused by mutations in a gene called PINK1.
The researchers, from the University of California in Los Angeles and
the Korea Advanced Institute of Science and Technology, explored the
effect on the equivalent gene in the fruit fly, Drosophila. Flies with
a mutant form of the gene suffered defects in the mitochondria.
Cell damage
This appeared to cause serious damage to muscle cells, which led to
movement problems.
It also appeared to lead to trigger degeneration of cells that
transport a key chemical, dopamine, around the brain.
Parkinson's has been linked to a shortage of dopamine, which is known
to play a key role in the co-ordination of movement.
Both muscle cells and dopamine-transporting brain cells consume large
amounts of energy, and thus are more reliant than most on healthy
mitochondria.
The researchers also produced evidence suggesting that the PINK1
protein has a knock-on effect on another molecule - Parkin - which has
also been implicated in Parkinson's.
They suspect that the two proteins both play an important role in
keeping the mitochondria healthy.
New treatments
The researchers say their work could ultimately lead to new
treatments.
Writing in the journal, they say: "Our findings will lead to the
development of better and effective treatment strategies for AR-JP and
possibly other forms of Parkinson's disease."
Kieran Breen, director of research at the Parkinson's Disease
Society, said cases of inherited Parkinson's were relatively rare
compared to the non-inherited form of the disease.
But he added: "The identification and study of such Parkinson's
disease-causing genes can be of great value in understanding the
disease processes, which may be relevant to all patients."
Mr Breen said uncovering how nerve cells that produce dopamine die
would be crucial to gaining a better understanding of Parkinson's, and
developing new treatments. Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/4967892.stm
Published: 2006/05/06 23:19:49 GMT
© BBC MMVI
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