Stem cell trial offers hope for vision patients
WASHINGTON | Mon Nov 22, 2010 6:19pm EST WASHINGTON (Reuters) - Christopher Goodrich of Portland, Oregon, can't wait to stick a needle in his eye. Goodrich hopes to be one of the first patients enrolled in clinical trial that just got a go-ahead from the U.S. Food and Drug Administration, only the second trial approved anywhere in the world to test human embryonic stem cells in people. Advanced Cell Technology, a small Massachusetts-based biotechnology company that has struggled to bring human embryonic stem cells from the lab to the clinic, will begin recruiting 12 patients in Oregon and Massachusetts with a rare eye condition called Stargardt's macular dystrophy. Goodrich, 55, retired last year from his job as coordinator for veteran's services at Portland State University when his Stargardt's macular dystrophy suddenly and inexplicably worsened. Like most patients, Goodrich had seen his vision get steadily worse since his young adult years. "Glasses help very, very little," Goodrich said in a telephone interview. "What macular degeneration is, you know that that center part of your eye that does all the fine tuning? The cells die. You know what a shotgun blast looks like? That is what I see. It's all over the place. I might see something out of the corner of my eye and turn my head and then I can't see it." It is infuriating and Goodrich would do anything to get better, even allow his eye doctor to poke a needle into his eye and infuse human embryonic stem cells that ACT hopes will take up residence and replace the missing cells. "I've made a list of all the things I would love to be able to do and all the things I would love to be able to see," Goodrich says. OTHER EYE DISEASE IN SIGHTS This is the most immediate promise of human embryonic stem cell research -- that these immature cells can be coaxed partly down the road to becoming a desired tissue type, and in the process get other cells growing and renewing. Advanced Cell Technology's product is a human embryonic stem cell trained to become a retinal cell. For this first clinical trial, only a few thousand of these cells will be injected into one eye of each volunteer, mostly to check to see that it is safe. ACT's Dr. Robert Lanza says the doctors taking part in the trial will be able to watch it unfolding in real-time, because it is possible to look into the eye and see the cells taking up residence in the retina. And it will be possible to continuously check the vision of the patients, to see if it is improving. ------------------------------------ Post message: prole...@egroups.com Subscribe : proletar-subscr...@egroups.com Unsubscribe : proletar-unsubscr...@egroups.com List owner : proletar-ow...@egroups.com Homepage : http://proletar.8m.com/Yahoo! Groups Links <*> To visit your group on the web, go to: http://groups.yahoo.com/group/proletar/ <*> Your email settings: Individual Email | Traditional <*> To change settings online go to: http://groups.yahoo.com/group/proletar/join (Yahoo! ID required) <*> To change settings via email: proletar-dig...@yahoogroups.com proletar-fullfeatu...@yahoogroups.com <*> To unsubscribe from this group, send an email to: proletar-unsubscr...@yahoogroups.com <*> Your use of Yahoo! Groups is subject to: http://docs.yahoo.com/info/terms/
