On Jul 6, 2006, at 12:55 PM, William Bug wrote:

In the context of the comment above, this is being addressed by trying to establish a foundational ontology for biomedical reality and an ontology of relations ([]).  I realize we went through this debate of the foundational ontology a few weeks back, but a fairly specific path is already being followed by the folks working on the OBO Foundry


Ooops.

In my haste, juggling this with 3 other parallel tasks in the lab this afternoon, I missed the references here, though I expect many on this list are aware of what I'm referring to.


Relations in biomedical ontologies
Barry Smith, Werner Ceusters, Bert Klagges, Jacob Köhler, Anand Kumar, Jane Lomax, Chris Mungall, Fabian Neuhaus, Alan L Rector  and Cornelius Rosse
Genome Biology 2005, 6:R46     doi:10.1186/gb-2005-6-5-r46

Basic Formal Ontology (SNAP/SPAN)

Biodynamic Ontology

The Ontology of Biomedical Reality


Please note the unifying factor for all of the above - beyond the formalisms presented - is Dr. Barry Smith (http://ontology.buffalo.edu/smith/).

Despite the debates that continue on this topic, over the past 2 years, this body of work has had a very powerful influence over a wide swarth of work in large-scale, field-wide, biomedical KR/KD, so it's worth keeping it on our radar. I would stress this influence extends well beyond the realm of creating explicit, formal ontological frameworks to support complex, automated reasoning but is targeting much more basic levels of formal semantic representation - such as semantically-based, biomedical data integration - I believe to be directly relevant to several of the discussion threads across the W3C SW HCLSIG lists.

Cheers,
Bill


Bill Bug
Senior Analyst/Ontological Engineer

Laboratory for Bioimaging  & Anatomical Informatics
www.neuroterrain.org
Department of Neurobiology & Anatomy
Drexel University College of Medicine
2900 Queen Lane
Philadelphia, PA    19129
215 991 8430 (ph)
610 457 0443 (mobile)
215 843 9367 (fax)


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