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From: "kc28" <[EMAIL PROTECTED]>
Date: December 6, 2006 10:41:08 PM EST
To: "Alan Ruttenberg" <[EMAIL PROTECTED]>
Cc: "Tim Clark" <[EMAIL PROTECTED]>, [EMAIL PROTECTED], "Matthias Samwald" <[EMAIL PROTECTED]>, [EMAIL PROTECTED], [EMAIL PROTECTED], [EMAIL PROTECTED], [EMAIL PROTECTED], "Eric Neumann" <[EMAIL PROTECTED]>, "Ivan Herman" <[EMAIL PROTECTED]>, "Jonathan A Rees" <[EMAIL PROTECTED]>, [EMAIL PROTECTED], [EMAIL PROTECTED], [EMAIL PROTECTED], [EMAIL PROTECTED], [EMAIL PROTECTED], [EMAIL PROTECTED], [EMAIL PROTECTED], "Susie Stephens" <[EMAIL PROTECTED]>, "Vipul Kashyap" <[EMAIL PROTECTED]>, "June Kinoshita" <[EMAIL PROTECTED]>, "Elizabeth Wu" <[EMAIL PROTECTED]>, "Tonya Hongsermeier" <[EMAIL PROTECTED]>
Subject: Re: Another "one" liner

Hi,

Sorry, I’m falling behind in terms of answering emails as I’ve been having a very heavy teaching schedule this week (I’m also a little bit sick). Anyway, I received the following one-liners:

Vipul: Present a vision of the Bench to Bedside and the value proposition provided by SW Technologies through use case examples. Ivan and Helen: This is a vision paper for the application of semantic web technology in biomedical research and development. Joanne: HCLSIG's role in facilitating the vision of translational medicine (aka bench to bedside) Matthias: A paper that is 1/3 about the vision, 1/3 about the work we have done so far and 1/3 a review of our thoughts about the pros/ cons of Semantic Web technologies." Scott: A clear report explaining the HCLS mission and progress to date. Alan: HCLSIG: Exploring the challenges of using and sharing information in a semantic web connecting the life sciences.

Based on the above one-liners, I have a question about the following terms:

HCLS
bench to bedside
biomedical
translational medicine

Do they mean the same thing? Are they belong to one discipline (http://www.amia.org/meetings/f02/call/intro.html)? For example, when we talk about bench to bedside, are we talking about translational informatics (intersection of bioinformatics and medical informatics) or the range of activities in bioinformatics and medical informatics. My impression is that the type of activities that are going on within HCLS involve bioinformatics, medical informatics and their bridge. So when we use the phrase “bench to bedside”, I think we should define clearly what it means.

Personally I prefer a balanced and synergistic approach to describing different aspects of our HCLS group, including mission, vision, progress, use cases, challenges, and semantic web (introduction and strength and weakness). This may help different authors who have different backgrounds/interests to contribute. We can write up to 20 pages (in BMC format). When we talk about vision, I think the vision should not be too ambitious. It should be a deliverable/realistic vision (not a hype) given the strengths and limitations of SW. It’s better to show some results (albeit preliminary) to support our claims. We should avoid making claims that cannot be substantiated. We have about two weeks left.

Best,

-Kei


Alan Ruttenberg wrote:

I'm not great with one liners. Perhaps:

HCLSIG: Exploring the challenges of using and sharing information in a semantic web connecting the life sciences.

But the paragraph below is a better captures it. Think of it as a really long line :)
(hence the quotes around "one")

-Alan

On Dec 5, 2006, at 9:22 AM, kc28 wrote:

Hi Alan,

Can you provide a one-line goal also? For example, description of HCLS activities in applying semantic web technologies ...

Best,

-Kei

Alan Ruttenberg wrote:

Here's a story that I think is both representative of who/where we are, and which creates a story that fits into the special issue.

Everyone in this group is in a science or health care support role of one kind or another. They collect and provide information and strive to make connections across domains because they think it will help work of their group. This paper describes their shared activities in applying semantic web technologies to see if that helps. It describes - The domains from which the information comes and the problems trying to be solved - Technology and experiments that have been tried to represent, link and manipulate that information - Problems that have been encountered, conceptual, social and technical - Some of the things that they hope will be possible if/when the program is widely adopted.

As such it is representative of the challenges that e-science practitioners will need to address when it comes to knowledge sharing and manipulation.








Eric Neumann, PhD
co-chair, W3C Healthcare and Life Sciences,
and Senior Director Product Strategy
Teranode Corporation
411 1st Avenue South, Suite 700
Seattle, WA 98104
+1 (781)856-9132
www.teranode.com


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