Hi Elizabeth,

Thanks a lot for the information. It seems to fit in the broad "cholinergic hypothesis"

http://www.ncbi.nlm.nih.gov/pubmed/16918347

It's interesting to know, as you pointed out, that the clinical trials for the same drug are in different phases in different countries. It would be great if we can integrate such clinical trial data across different countries.

Best,

-Kei

Elizabeth Wu wrote:
Hi Kei,

There is an entry in the Drugs in Clinical Trials section of Alzforum on
Huperzine A http://www.alzforum.org/drg/drc/detail.asp?id=53. The drug is
currently in Phase IV clinical trial in China and phase II in the US.  Its
proposed actions are linked to many of the AD hypotheses, and I would think
that if there are sources on research on herbs that could provide more
insight, it would be of interest to the community.

Best,

Elizabeth

Elizabeth Wu
Alzheimer Research Forum
-----Original Message-----
From: [EMAIL PROTECTED]
[mailto:[EMAIL PROTECTED] On Behalf Of
[EMAIL PROTECTED]
Sent: Sunday, May 25, 2008 10:41 PM
To: Tim Clark
Cc: M. Scott Marshall; public-semweb-lifesci@w3.org
Subject: Re: KB note


Hi Tim et al.,

I think it would be great if more details about SWAN can be added. The HCLS
ecosystem consists of scientists, patients, doctors, government agencies,
publishers, etc. Creating/maintaining a balance in this digital age across
national boundaries is challenging/interesting.

Speaking of national boundaries, I wonder if alternative medicine (e.g.,
herbal
medicine) would also be of interest to this community. For example,
Huperzine
is a drug derived from the herb Huperzia serrata. I also wonder if there are
hypotheses regarding the study of herbs in the possible treatment of
neurological diseases.

Thanks,

-Kei


Quoting Tim Clark <[EMAIL PROTECTED]>:

Hi Scott,

Your KB note lists no details about SWAN - we would like to see them
included.  I'll forward something to you in a separate email later
today.

Best

Tim

Tim Clark
Director of Informatics, MassGeneral Institute for Neurodegenerative
Disease
Instructor in Neurology, Harvard Medical School
617-947-7098 (mobile)

On May 23, 2008, at 6:59 PM, M. Scott Marshall wrote:

The KB note is ready for a last round of feedback and corrections.
We have until the end of the month to publish so please be speedy
with feedback. You can view the Editor's working draft at:
http://www.w3.org/2001/sw/hcls/notes/kb/
Thanks,
Scott

--
M. Scott Marshall
tel. +31 (0) 20 525 7522
http://staff.science.uva.nl/~marshall
http://adaptivedisclosure.org












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