Dear Helen,

I'd be very interested in how you get on. I can't see how to extract a SNOMED-CT ID from RxNorm in the navigator, but I'm sure it can be done from the dataset.

More generally, I'm interested why you didn't use drug names from something like Pubmed (I'm sure there's a reason - I just don't know what it is).

Thanks,

Matt

[EMAIL PROTECTED] wrote:

Ronald

I checked RxNav and it is a good tool to get most of information we needed for the COI test case.

I will check the mapping between RxNorm ingredients and SNOMED to see how we can get the link between, for example "anticoagulants" to detailed drug names in RxNORM.
Thanks for the pointer and good suggestions.

Helen




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        RE: [COI] CT#8 Drug Information Needed for Test Case Query


        






Helen,
Looking at RxNorm via RxNav _http://mor.nlm.nih.gov/download/rxnav/_
Here the brand names below can be mapped to ingredients.
Looking up the ingredients in SNOMED shows their classes. So it seems that adequately combining the two can do the job. Regards, Ronald
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Ronald Cornet, PhD                    email: [EMAIL PROTECTED]
dept. of Medical Informatics          phone: +31 (0)20 566 5188
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*From:* [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] *On Behalf Of [EMAIL PROTECTED]
Sent:* Wednesday, June 11, 2008 16:34*
To:* [EMAIL PROTECTED]
Subject:* [COI] CT#8 Drug Information Needed for Test Case Query


Eric

As a minimal requirement to get the test case working In the CT#8 [1], we need to identify the following drug information. I did some text search in your Medicaiton_DE.txt [2] file and found some examples of drug names under each category
*
1. Metfomin, Insulin secretagogue, or Alpha-glucosidase inhibitors* *
drug names: *Metformin, Repaglinide, Gliclazide, Glipizide, Acarbose, Miglitol *
2. Insulin therapy* *
drug names: *Aimsco Insulin Syringe, *
3. Rosiglitazone or Proglitazone* *
drug names: *Avandia, Actos *
4. corticosteriods treatment* *
drug names: *Prelone, Medrol, Deltasone, Kenalog, etc *
5.  weightloss drugs* *
drug names: *Xenical, Meridia, Tenuate, Tepanil, Adipex-P, Fastin, Phentermine HCl , etc *
6. nonsteroidal anti-inlammatory drugs* *
drug names: *Ibuprogen, Naproxen Sodium , Diclofenac Potassium, Diclofenac Sodium, etc *
7. anticoagulants* *
drug names: *Coumadin, Plavix, Heparin, etc *
8. uricosuric medication* *
drug names: *Benuryl, Benemid, Probalan, Anturane *
* Your Medication.DE file seems to contain drug name and package information, but as you can see, there is no "drug" class relationship that represents the above relationship. I doubt we can find such categorization relationship in RxNorm. For the demonstration purpose, we can construct a small "drug" ontology to cover the above concepts and drug names. But the ideal way is to use an existing and well developed drug ontology for this purpose.
Does anyone on the list know such ontology?

Kind Regards,


[1] http://esw.w3.org/topic/HCLS/ClinicalObservationsInteroperability/SPARQL8.html
[2] http://www.w3.org/2008/04/DiabeticPatientsDataSet/Medication_DE.txt

*
Helen Chen | **Agfa HealthCare*
Senior Researcher | HE/Advanced Clinical Applications Research
T  +1 519 746 6210 Ext.3186 | M  +1 519 498 6244

Agfa HealthCare Inc., 455 Phillip Street, Waterloo, ON N2L 3X2, Canada_
__http://www.agfa.com/healthcare/_
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