Although we didn't have time to implement this example before the C-SHALS meeting, as we discussed at our BioRDF call today, we will implement this example and include it in the BMC Bioinformatics paper (on query federation) that we're working on. Eric has updated his FeDeRate code so that performance has been improved significantly.

The receptor tables (in csv format) are listed at:

http://esw.w3.org/topic/HCLSIG_BioRDF_Subgroup/QueryFederation/iuphar_receptors

Eric, please use the "Class C" table and load it in your relational database. Also, Matthias and Rob will help in this implementation effort.

Cheers,

-Kei

Matthias Samwald wrote:
(Moving this discussion to the public mailing list)

To follow up the teleconference we just had...
Here is an example of finding links between DBpedia receptors and the IUPHAR receptor table:

* Look at http://dbpedia.org/resource/GABAB_receptor
* Look at property http://dbpedia.org/ontology/uniprot it has the values "O75899" and "Q9UBS5"
* Now look at the IUPHAR "Class C" spreadsheet
* You will find these exact identifiers in the "Human nucleotide" and "Human SwissProt" columns of the matching IUPHAR entry, respectively (that should be columns 8 and 10, if I counted right).

-> Mapping accomplished!

Note that only some of the receptors mentioned in http://neuroweb.med.yale.edu/res/senselab_receptor_to_DBpedia_mapping.owl can be mapped to IUPHAR with this procedure (not all receptors have sequence entries, because they are multimeric complexes). But for those entities where it works, we can create a federated query that spans NeuronDB (OWL file), DBpedia (SPARQL endpoint), IUPHAR (direct query of relational tables / CSV), PDSP KiDB (OWL generated from CSV) and others -- quite useful and a good show case for query federation.

Hope that helps,
Matthias Samwald

DERI Galway, Ireland
http://deri.ie/

Konrad Lorenz Institute for Evolution & Cognition Research, Austria
http://kli.ac.at/




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