Hi, Because you mentioned about ontology (GO) in the context of relational databases I thought you may be interested in looking into our site where we incorporated over 99 large ontology into a relational database. Most of these large ontology were originally obtained from GO. http://xpdb.nist.gov/bioroot/bioroot.pl The above Web resource allows a user to selectively query and download custom made section of any of the ontology for his/her needs in simple Excel format Below is a link to a recent BMC paper where we discuss a new approach for building and reasoning ontology in a federated set up. http://www.biomedcentral.com/1471-2105/12/487
An example of this approach for cell image data is in http://sbd.nist.gov/image/cell_image.html Similar approach for building and reasoning rule-based ontology for chemical structures are implemented for several million compound in the URL shown below http://xpdb.nist.gov/chemblast/pdb.pl Let me know if you have any comments T N Bhat From: binchenindi...@gmail.com [mailto:binchenindi...@gmail.com] On Behalf Of bin chen Sent: Thursday, April 05, 2012 4:10 PM To: public-semweb-lifesci Subject: reasoning on gene ontology Hi, Does anyone perform some reasoning using gene ontology? Any intereting story to share? I recently ran reasoning based on extended GO relations [1], and found that the triples doubled after reasoning. I was also aware of some queries are not able to be performed in relational database. but I havenot found very interesing cases to utlize the inferred results. Any reference? Thanks. Best, Bin [1] http://www.geneontology.org/GO.ontology-ext.relations.shtml -- Bin Chen PHD student, Informatics, Indiana University at Bloomington http://cheminfo.informatics.indiana.edu/~binchen
