I would also be interested in extending this with data extracted from
European product labels. Compared to the US and Dailymed, this is far
trickier. The data is not openly available for many countries, content has
different languages, and structured product labels are even harder to come
by.
A Viennese startup called http://www.diagnosia.com/de/ recently made package
insert texts from 12 European countries openly available. I plan to contact
them and see if they would also be interested in cooperating with research
projects. We might not end up with a resource that can be shared without
restrictions, but at least we could end up with something that allows us to
run SPARQL queries for analysis and research.
Other ideas for how such a multilingual, pan-European ressource are welcome!
Cheers,
Matthias
Hi, Richard,
Very nice work. Building the linked data source for SPLs is very important
for facilitating its wide use. It is impressive that you keep the source
updated once per week.
As you have pointed out that the SPLs are semi-structured, the combination
of NLP and standard terminologies will be crucial for producing structured
data out of the SPLs. As you know, our team at Mayo Clinic is
investigating
the SPLs from the perspective of Adverse Drug Events. We would like to
collaborate to see whether we could link our ADEpedia data
(http://adepedia.org) with your LinkedSPLs.
The following are our preliminary works,
1) Jiang G, Solbrig H, Chute CG. ADEpedia: a scalable and standardized
knowledge base of Adverse Drug Events using semantic web technology. AMIA
Annu Symp Proc. 2011;2011:607-16. Epub 2011 Oct 22.
http://www.ncbi.nlm.nih.gov/pubmed?term=adepedia
2) Zhu Q, Jiang G, Chute CG. Profiling Structured Product Labeling using
RxNorm and NDF-RT. ICBO 2012 Workshop (to be held in July 21-25, 2012).
Best regards,
Guoqian
Guoqian Jiang, M.D., Ph.D.
===========================================
Assistant Professor of Medical Informatics
Division of Biomedical Statistics & Informatics,
Mayo Clinic College of Medicine
200 First Street, SW,
Rochester, MN, 55905
Tel: 1-507-266-1327
Fax: 1-507-284-0360
Email: jiang.guoq...@mayo.edu
===========================================
On 6/14/12 12:47 PM, "Richard Boyce" <rd...@pitt.edu> wrote:
Minutes from BioRDF/LODD telcon Monday 06/12/2012
Rich Boyce (University of Pittsburgh) presented "LinkedSPLs - a
dynamically updated and comprehensive linked data node for US drug
package inserts"
Link to his slides:
<http://www.slideshare.net/boycer/linkedsplsinitialhclspresentation06082012>
Summary of discussion:
Richard: Purpose of presenting is to attract collaborators...consider
Linked Structured Product Labels an important data resource to keep up
to date and improved, hopefully with partners.
Richard: Structured Product Labels are the standard in the U.S.
Medscape, Micromedex echo product labels and add information that is
missing. If a recent IOM report (http://tinyurl.com/cxovshm) is acted
on, we should see some progress in how the product labels are formed in
the next few years
ericP: q+ to ask if the SPLs reflect the areas of concensus and that
affects the degree to which not being on the SPL indicates variation of
information from the various resources
Richard: (answering EricP): Interesting question. Warfarin is an example
of how consensus from the community ended up in the product label. Often
the information is not complete and it is left up to third parties to
complete - dynamic process.
Richard: FDA wrote laws the dictate the types of claims that should be
present in each section. This gives us an opportunity to link to related
resources such as for evidence.
Richard: FDA wrote laws the dictate the types of claims that should be
present in each section.
..This gives us an opportunity to link to related resources such as for
evidence.
..[slide8]DailyMed is the public source of SPLs
..[slide9] "SPL IDs are not static, so a label's URL may change if
..the label is updated. However, DailyMed provides permanent
..URLs to view or download the latest version of an SPL²
Richard: LinkedSPLs started with Anja's PHP for DailyMed and ported to
python
EricP: correcting for multiple active ingredients require modeling
changes?
Richard: Modeling changes
UNII -
Unique Ingredient Identifier
sounds like Unicode when spoken!
CODE: http://swat-4-med-safety.googlecode.com/svn/trunk/linkedSPLs/
JoanneLuciano Health Care Delivery Grants from ???
Simon Lee: Maybe use for AHRQ grants
JoanneLuciano NIN NLM grants
JoanneLuciano I'm thinking this can be linked with Safety-Code.org
Richard: Think it's a little early for AHRQ grants, more research
necessary
Simon: agree.
Simon: need working prototype.
Simon Lin - Marshfield Clinic
michel DrugBank is the best to link to, i think
michel they then link out to many other sources
JoanneLuciano safety-code.org
michel BTW - I've built a new parser for drugbank
michel
http://bio2rdf.semanticscience.org:8022/describe/?url=http%3A%2F%2Fbio2rdf.org
%2Fdrugbank%3ADB00975&sid=5
michel we're in the process of adding this to bio2rdf
mscottm asks michel - adding what?
ericP zakim, please disconnect ericP
Zakim EricP is being disconnected
gamble @boycer I'm interested in data quality / Minimum information
checklist validation potential for this data. Versioning is also
interesting. I don't have a mic so I'll follow up by email.
michel adding my parse of drugbank to bio2rdf
