Have you tried re-setting sys.argv before running setup (aka sys.argv=['setup.py','--build'] ; run setup.py,local )? If I'm understanding the help for the pymol run command correctly, you'd want to use either local or module (so that the global namespace doesn't confuse things).
Now that finaly got me closer to the solution! :-) This way I could start the setup.py installation. Thx! But now I'm facing another problem: PyMOL>sys.argv=['setup.py','build'] PyMOL>run setup.py, local running build running build_py copying MySQLdb\release.py -> build\lib.win32-2.4\MySQLdb running build_ext Traceback (most recent call last): File "C:\Program Files\DeLano Scientific\PyMOL/modules\pymol\parser.py", line 291, in parse parsing.run_file(exp_path(args[nest][0]),pymol_names,{}) File "C:\Program Files\DeLano Scientific\PyMOL/modules\pymol\parsing.py", line 407, in run_file execfile(file,global_ns,local_ns) File "setup.py", line 19, in ? setup(**metadata) File "C:\Program Files\DeLano Scientific\PyMOL\py24\lib\distutils\core.py", line 166, in setup raise SystemExit, "error: " + str(msg) SystemExit: error: The .NET Framework SDK needs to be installed before building extensions for Python. Where should I install the .NET Framework? Bye DeVill P.S.: sorry for the previous empty E-mail... my client mesd things up a bit :-*