Hi,

You can install the open source version 2.5 of PyMOL using homebrew and it will 
be M1 native (see https://brew.sh)

But frankly, the intel version is already so fast with rosetta2 on the M1 that 
it does not worth it except if you do really fancy stuff.

Florian

> On 6 Dec 2021, at 08:00, Chris Swain via PyMOL-users 
> <pymol-users@lists.sourceforge.net> wrote:
> 
> Hi,
> 
> Thanks all will give it a try
> 
> Cheers,
> 
> Chris
> 
>> On 6 Dec 2021, at 06:08, Jarrett Johnson <jarrett.john...@schrodinger.com 
>> <mailto:jarrett.john...@schrodinger.com>> wrote:
>> 
>> IIRC when we tried with Rosetta2, PyMOL was still faster (about 2x I think) 
>> than the previous x86. Your mileage may vary.
>> 
>> Best,
>> Jarrett J
>> 
>> On Mon, Dec 6, 2021 at 12:46 AM Xin Yu <xinyu18...@gmail.com 
>> <mailto:xinyu18...@gmail.com>> wrote:
>> It looks like while you can’t run it natively on M1, maybe you can do it 
>> through rosetta2 translation via Conda install?
>> See here: https://pymol.org/2/support.html? 
>> <https://pymol.org/2/support.html?>
>> Supported platform states M1 with rosetta2. Perhaps with some penalty for 
>> efficiency though. Anyone tried?
>> 
>> Sent from my iPhone
>> 
>>> On Dec 5, 2021, at 10:27 PM, Jarrett Johnson 
>>> <jarrett.john...@schrodinger.com <mailto:jarrett.john...@schrodinger.com>> 
>>> wrote:
>>> 
>>> 
>>> Hi Chris,
>>> 
>>> We haven't released any official Incentive PyMOL builds yet for M1 ARM mac 
>>> yet but it's on our radar to do so soon.
>>> 
>>> Best,
>>> 
>>> Jarrett J
>>> 
>>> On Sun, Dec 5, 2021 at 2:09 PM Chris Swain via PyMOL-users 
>>> <pymol-users@lists.sourceforge.net 
>>> <mailto:pymol-users@lists.sourceforge.net>> wrote:
>>> Hi,
>>> 
>>> Is there a build of PyMOL for M1 Macs yet?
>>> 
>>> Cheers,
>>> 
>>> Chris
>>> 
>>> 
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>>> 
>>> -- 
>>> Jarrett Johnson | Senior Developer, PyMOL
>>> 
>>> _______________________________________________
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>> 
>> -- 
>> Jarrett Johnson | Senior Developer, PyMOL
>> 
> 
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