I know this is a FAQ, however I haven’t been able to make any of the standard 
answers work for me. Here’s the situation:

- using PySide2 5.12.2
- I have an object (QMainWindow subclass) that contains most of the code for my 
application
- One of the functions that runs in response to user input takes around 2 
seconds to run. The GUI obviously freezes during this time (BAD!)
- Said function needs to access and modify several large variables (pandas data 
frames) from the main object

So here’s the problem: If I run this function as a separate (python) thread, 
that doesn’t help - the GUI is still frozen. I’m thinking this is due to the 
GIL, but I could be wrong about that. Running under the multiprocessing module, 
however, doesn’t appear to be an option due to the number and size of the data 
structures that the function needs to modify, and if I try just to see what 
happens, the process actually crashes.

So what are my options here? How can I keep the GUI responsive while this 
function runs, without being able to spin it off as a separate process? Or is 
the only option going to be to completely rip apart the function and try to 
re-build it in such a way that it can, somehow, still access the memory from 
the main thread, while doing the processing in a separate function?
---
Israel Brewster
Software Engineer
Alaska Volcano Observatory 
Geophysical Institute - UAF 
2156 Koyukuk Drive 
Fairbanks AK 99775-7320
Work: 907-474-5172
cell:  907-328-9145

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