Ned Deily added the comment:

Just a reminder that we support configurations where there are both big-endian 
and little-endinan binaries in the *same* executable file: for example, Mac OS 
X 32-bit-only universal binaries (.so, .dylib, .exe) contain both i386 and ppc 
code in the same file.  So any -endian differences must remain isolated to C 
code or be dynamically tested at execution time in Python code. And ./configure 
time tests can be problematic.  (The proposed patch doesn't have that problem 
but it might be an issue later in tests.)

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nosy: +ned.deily

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<http://bugs.python.org/issue16166>
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