Stefan Behnel <stefan...@behnel.de> added the comment:

FWIW, a PGO build of Py3.7 is now about 20% *faster* here than my Ubuntu 16/04 
system Python 2.7, and for some (probably unrelated) reason, the system Python 
3.5 is another 2% faster on my side.

IMHO, the only other thing that seems obvious to try would be to inline the 
unpacking of single digit PyLongs into sum(). I attached a simple patch that 
does that, in case someone wants to test it out. For non-PGO builds, it's about 
17% faster for me. Didn't take the time to benchmark PGO builds with it.

----------
versions:  -Python 3.5
Added file: https://bugs.python.org/file47748/unpack_single_digits.patch

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