STINNER Victor <vstin...@python.org> added the comment:

> Should we stop the work until the overhead is measured?

Can you try to measure the _abc._abc_instancecheck() and 
_abc._abc_subclasscheck() functions performance before/after your change? 
Functions like register() are rarely call, so I don't care much of their 
performance (I expect a small overhead or no overhead).

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Python tracker <rep...@bugs.python.org>
<https://bugs.python.org/issue40077>
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