STINNER Victor <vstin...@python.org> added the comment:

> Some changes have a negative impact on "single threaded" Python application. 
> Even if the overhead is low, one option to be able to move faster on this 
> issue may be to add a new temporary configure option to have an opt-in build 
> mode to better isolate subinterpreters. (...)

I created bpo-40514: "Add --experimental-isolated-subinterpreters build option".

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Python tracker <rep...@bugs.python.org>
<https://bugs.python.org/issue40512>
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