As explained in PEP 560, creation of Generic subclasses is much slower (~7x on my machine). My guess is that a limited number of applications actually need Generic classes at "production" runtime (i.e. when not under analysis of mypy or IDE).
I propose a special class that will alias typing.Generic whenever typing.TYPE_CHECKING == True and a no-op stub otherwise. Best Regards, Ilya Kulakov
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