Python.org lists PORPIG (PORtland Python Intrest Group) but the site that it points to no longer seems to represent that. Also, when I looked into going to a meeting a while back, the last one listed was some time in 2004. I will put this out there though, if someone wants to start a PIG back up for Portland I would certainly be interested. I am at least one Python developer living in the Portland area. The web contains evidence of others as well. In general there is a fairly large software development presence in Portland, especially around Open Source.
-- http://mail.python.org/mailman/listinfo/python-list