I can confirm this, I am getting very slow read performance when reading a smaller 20 MB file.
- Python 2.5 takes 0.4 seconds - Python 3.0 takes 62 seconds fname = "dmel-2R-chromosome-r5.1.fasta" data = open(fname, 'rt').read() print ( len(data) ) -- http://mail.python.org/mailman/listinfo/python-list