I found that Head First Python gives a really good introduction to Django. It's definitely a beginners book, as are all of the Head First books, but it still teaches the basics in a very good manner.
If you're very knowledgeable with Python, you can skip the first few chapters (or read through them as a refresher), and eventually you'll get to some chapters where you do some web design with Django. It doesn't go REALLY into depth here, but you have to start somewhere, right? I hope that this helps! -- http://mail.python.org/mailman/listinfo/python-list
