basically, you can just stack an outer vertical box sizer with two items and in the upper "slot" you put a horizontal box sizer with your two buttons and in the bottom slot you put the big button
hope this helps /Simon ps. as this is a wxpython related question, you might get better answers on the wxpython mailinglist (but afaik, this is the way this particular thing is done). -- http://mail.python.org/mailman/listinfo/python-list
