IMHO, the easier alternative for building GUI apps with Python is PythonCard. It is based on wxWindows, and it lets you build gui apps by dragging and dropping widgets on a form, just like VB or Delphi. It is very high level and very easy to learn and use.
http://pythoncard.sourceforge.net/ Another alternative, also based in wxWindows, is Boa Constructor, but I wouldn't recomend it over Pythoncard. Good luck! Luis -- http://mail.python.org/mailman/listinfo/python-list