wxGlade is built into SPE the Python IDE.
http://www.stani.be/python/spe/blog/

I personally use Wax - http://sf.net/projects/waxgui

This is another layer *on top* of wxPython, but makes it much nicer to
program with.

For *small* GUIs you're probably better using Tkinter, which can be
made to look nice - and has the easiest learning curve (and a much
lower installation overhead than the others, because it comes with most
distributions of Python).

All the best,

Fuzzyman
http://www.voidspace.org.uk/python/index.shtml

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