Some of the reasons are explained here: http://www.amk.ca/python/writing/why-not-zope.html
I am using the last Zope (2.8.4) at work, and the situation is slightly better now than in the past, but only slightly. Zope 3 looks better, but I am not sure how much better. Michele Simionato -- http://mail.python.org/mailman/listinfo/python-list