There is also TurboGears, which (IMO) is greatness in the making. Though unfortunately, the documentation is still catching up to the greatness. I'm using it and loving it, though.
http://www.turbogears.org DJango is great for content management. TurboGears is (IMO) a more generalized framework. It all depends on what kind of site you are wanting to create. -- http://mail.python.org/mailman/listinfo/python-list
