Hi Jeff,

Can you check this: 
https://qgis.nl/2021/11/05/qgis-on-windows-oops-could-not-load-qgis_app-dll-message/

With us it was a opencl.dll which is wrongly copied/not removed by Windows (see 
links in the post).

Short version: make sure you have the good copy of opencl.dll either in the 
QGIS install dir OR in the c:/windows/system32 directory. See 
https://github.com/qgis/QGIS/issues/44806#issuecomment-908976764 for more info 
about it.

HTH,

Richard Duivenvoorde

On 7/6/22 03:31, Jeff Sonnentag via Qgis-user wrote:
Extra info. . . .

Uninstalled the previous version (3.22.7-1) same as always and then installed 
3.22.8-3 (freshly downloaded QGIS-OSGeo4W-3.22.8-3.msi 
<https://download.qgis.org/downloads/QGIS-OSGeo4W-3.22.8-3.msi>).  Error never 
has appeared before when doing the same kind of uninstall of previous version and 
install of latest LTR. . . .

*From:* Qgis-user <qgis-user-boun...@lists.osgeo.org> *On Behalf Of *Jeff 
Sonnentag via Qgis-user
*Sent:* Tuesday, July 5, 2022 6:25 PM
*To:* qgis-user <qgis-user@lists.osgeo.org>
*Subject:* [Qgis-user] Burned by QGIS again - Windows 10 QGIS 3.22.8

Well, burned by a QGIS installation again, and this time a LTR version late in 
the game.

Windows 10 and all previous installations have started up at least fine from 
all previous installations and updates.  Who knows which of the NUMEROUS 
environmental paths it doesn’t think is right.  Another non-informative error 
message. . . .


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