Hmm...I see. I think I will give a try to the univariate analysis nonetheless...I intend to catch the p-values for each gene and select the most significant from these...I have seen it in several papers.
Best Regards, Eleni On Feb 13, 2008 2:59 PM, Terry Therneau <[EMAIL PROTECTED]> wrote: > What you appear to want are all of the univariate models. You can get > this > with a loop (and patience - it won't be fast). > > ngene <- ncol(genes) > coefmat <- matrix(0., nrow=ngene, ncol=2) > for (i in 1:ngene) { > tempfit <- coxph(Surv(time, relapse) ~ genes[,i]) > coefmat[i,] <- c(tempfit$coef, sqrt(tempfit$var)) > } > > > However, the fact that R can do this for you does not mean it is a good > idea. > In fact, doing all of the univariate tests for a microarray has been shown > by > many people to be a very bad idea. There are several approaches to deal > with > the key issues, which you should research before going forward. > > Terry Therneau > > [[alternative HTML version deleted]] ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.