On Jun 28, 2011, at 6:26 PM, David Winsemius wrote:


On Jun 28, 2011, at 5:46 PM, Trey Batey wrote:

Hello.

I am trying to write an R function to plot the survival function (and
associated hazard and density) for a Siler competing hazards model.
This model is similar to the Gompertz-Makeham, with the addition of a
juvenile component that includes two parameters---one that describes
the initial infant mortality rate, and a negative exponential that
describes typical mortality decline over the juvenile period.  The
entire hazard is expressed as


h(x) = a1*exp(-b1*x)+a2+a3*exp(b3*x)


I've had success in plotting the curves using the following function:


I modified your function to have named parameters:

############################################################
siler<-function(a1=0.1, b1=0.5,a2=0.001,a3=0.003,b3=0.05) # model Siler parameters
{
  sil=function(t)
    {       h.t<-a1*exp(-b1*t)+a2+a3*exp(b3*t)
      S.t<-exp(-a1/b1*(1-exp(-b1*t))-a2*t+a3/b3*(1-exp(b3*t)))
      d.t<-S.t*h.t

      #return(d.t)
      return(S.t)    # returns the survival function
      #return(h.t)
    }

  t=seq(0,100,0.01)
  plot(t,sil(t),ylim=c(0,1),type='l',main="Siler model of mortality:
Wood et al. (2002, Figure
7.4)",cex.main=0.9,cex.lab=0.8,cex.axis=0.75,ylab='S(t)',xlab='Age
(years)')    # reproduces Figure 7.4 from Wood et al. (2002)

}

siler()
#########################################################################

How can I modify the function so that I can plot curves using
published Siler parameters I have already compiled into a dataframe
(below)?

names<-c("Hadza","Ache")
a1<-c(0.351,0.157)
b1<-c(0.895,0.721)
a2<-c(0.011,0.013)
a3<-c(0.0000067,0.000048)
b3<-c(0.125,0.103)


cbind outputs a matrix and the presence of character values means all your numbers are now character.... bad programming practice. Fix is here:

> sil.anthro[, 2:6] <- sapply(sil.anthro[, 2:6], function(x) as.numeric(as.character(x)) )
> str(sil.anthro)
'data.frame':   2 obs. of  6 variables:
$ names: Factor w/ 2 levels "Ache","Hadza": 2 1
$ a1   : num  0.351 0.157
$ b1   : num  0.895 0.721
$ a2   : num  0.011 0.013
$ a3   : num  6.7e-06 4.8e-05
$ b3   : num  0.125 0.103

> with( sil.anthro[1, -1], siler(a1=a1,b1=b1,a2=a2,a3=a3,b3=b3) )
> with( sil.anthro[2, -1], siler(a1=a1,b1=b1,a2=a2,a3=a3,b3=b3) )

Seems to work.

--
David.


For example, how can I modify the function above to produce a curve
for the a specific group (e.g., Hadza, Ache...) or multiple groups on
one graph?  Thanks.

Could use names as index
with( sil.anthro[sil.anthro$names=="Hadza", ],
               siler(a1=a1,b1=b1,a2=a2,a3=a3,b3=b3) )

And maybe even clearer would be:
> row.names(sil.anthro) <- sil.anthro$names
> with( sil.anthro["Hadza", ], siler(a1=a1,b1=b1,a2=a2,a3=a3,b3=b3) )

You probably should have done that originally as:

sil.anthro<-data.frame(a1=a1,b1=b1,a2=a2,a3=a3,b3=b3)
row.names(sil.anthro) <- names

(But even better woulbe to choose a 'name' other than 'names'.)



--
David Winsemius, MD
West Hartford, CT

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David Winsemius, MD
West Hartford, CT

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PLEASE do read the posting guide http://www.R-project.org/posting-guide.html
and provide commented, minimal, self-contained, reproducible code.

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