Dear R-user,
I'm having some difficulty with working PFIM 3.2, a package for
implementing population PK/PD in R. I wish to evaluate the determinant of
Fisher information matrix each time with successive dose from a pre defined
sequence of doses and want to store those values in a vector. It's
important to note that in my 'stdin.r' file, dose<-c(u) and each time u is
to be replaced as I said. I think a quick look on the following R codes
will give a more clearer picture of the objective:
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directory<-"F:\\PFIM3.2_examples\\experiment" # working directory
directory.program<-"F:\\PFIM3.2.2\\PFIM3.2.2\\PFIM3.2.2\\Program" #
program directory
true.dose<-seq(0,10,0.5) # predefined sequence of doses
deter=c() # to store determinant values
for (i in 1:length(true.dose) {
u<-true.dose[i]
source("F:\\PFIM3.2.2\\PFIM3.2.2\\PFIM3.2.2\\Program\\LibraryPK.r")
source("F:\\PFIM3.2_examples\\experiment\\model.r")
source("F:\\PFIM3.2_examples\\experiment\\stdin.r")
source("F:\\PFIM3.2_examples\\experiment\\PFIM3.2.r")
res<-PFIM()
deter[i]<-res$determinant
}
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But it's not working anyway and of course showing some error messages.
I have attached the the associated files.
Any suggestion in this regard will help me a lot.
Thank you very much for the patience!
Regards,
Jamil.
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