Thanks!
I tried already. Still the same error message...

wishes
Gunther
----- Original Message ----- From: "ONKELINX, Thierry" <[EMAIL PROTECTED]>
To: "Gunther Höning" <[EMAIL PROTECTED]>; <[email protected]>
Sent: Tuesday, July 01, 2008 3:08 PM
Subject: RE: [R] Regression and fitting



Try to set your own starting values. Use the values that you would expect for S0, mu and sigma.

HTH,

Thierry


----------------------------------------------------------------------------
ir. Thierry Onkelinx
Instituut voor natuur- en bosonderzoek / Research Institute for Nature and Forest Cel biometrie, methodologie en kwaliteitszorg / Section biometrics, methodology and quality assurance
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9500 Geraardsbergen
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tel. + 32 54/436 185
[EMAIL PROTECTED]
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~ Sir Ronald Aylmer Fisher

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~ Roger Brinner

The combination of some data and an aching desire for an answer does not ensure that a reasonable answer can be extracted from a given body of data.
~ John Tukey

-----Oorspronkelijk bericht-----
Van: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED] Namens Gunther Höning
Verzonden: dinsdag 1 juli 2008 14:41
Aan: [email protected]
Onderwerp: [R] Regression and fitting

Dear list,

I have some values like
Time 2 4 8 24 48 72

UTR 82543 169105 207615 96633 31988 7005
UTRs 82687 172934 205541 101842 31898 6950
of a twice repeated meassurement.

I know that the underlying function is of :

f(x) =  SO/(sqrt(2*pi)*sigma *x) * exp(-(S0*ln x - mu)^2/(2*sigma^2)).

How can I determine the value of S0, sigma and mu.

I tried nls:

lognormal <- function(x,S0,sigma,mu) {S0/(sqrt(2*pi)*sigma *x) *
exp(-(S0*log (x) - mu)^2/(2*sigma^2))}
x <- rep(c(2,4,6,24,48,72),2)
y <-
c(82543,169105,207615,96633,31988,7005,82687,172934,205541,101842,31898,6950
)
dat <- data.frame(x,y)
regfit <-  nls(y ~ lognormal(x,S0,sigma,mu) ,data =dat)


Output:

Error in nlsModel(formula, mf, start, wts) :
       singular gradient matrix at initial parameter estimates
Warning message:
No starting values specified for some parameters.
Intializing 'S0', 'sigma', 'mu' to '1.'.
Consider specifying 'start' or using a selfStart model in: nls(y ~
lognormal(x, S0, sigma, mu), data = dat)

Can anybody help on this topic please ?


Gunther

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