Boy are you confused.  This has nothing at all to do with substitution.

Instead do

        test <- with(fc,ave.fc[match(diff_mirs_list,Probe)])

        cheers,

                Rolf Turner

On 7/11/2008, at 11:46 AM, Iain Gallagher wrote:

Hello list.

I have a vector of values:

eg

head(diff_mirs_list)
[1] "hsa-miR-26b" "hsa-miR-26b" "hsa-miR-23a" "hsa-miR-27b" "hsa- miR-29a"
[6] "hsa-miR-29b"

and I would like to conditionally replace each value in this vector with a number defined in a dataframe:

fc
             Probe ave.fc
1       hsa-let-7a   1.28
2      hsa-miR-100   1.47
3  hsa-miR-125a-5p   1.31
4   hsa-miR-140-3p   1.28
5      hsa-miR-143   1.98
6  hsa-miR-193a-3p   1.37
7     hsa-miR-193b   1.48
8      hsa-miR-195   1.16
9      hsa-miR-214   1.22
10     hsa-miR-23a   1.21
11     hsa-miR-26b   1.13
12     hsa-miR-27b   1.37
13     hsa-miR-29a   1.24
14     hsa-miR-29b   1.69
15     hsa-miR-30b   1.16
16     hsa-miR-424   1.42
17  hsa-miR-768-3p   1.48
18  hsa-miR-886-3p   1.43
19     hsa-miR-933   1.23

ie every hsa-let-7a in the diff_mirs_list is replaced by 1.28, hsa- miR-100 by 1.47 etc etc

I have tried to make a loop to use gsub eg

for (i in 1:nrow(fc)){
+ test<-gsub(fc[i,1], fc[i,2], diff_mirs_list)
}

but this obviously passes the unchanged vector to gsub each time and so I get back my 'test' vector with only hsa-miR-933 changed. Could someone help me out with this please.

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