On Sep 25, 2009, at 8:33 PM, Lars Bishop wrote:

Dear R experts,

The lrm function in the Design package can perform penalized (Ridge)
logistic regression. It is my understanding that the ridge solutions are not equivalent under scaling of the inputs, so one normally standardizes the inputs. Do you know if input standardization is done internally in lrm or I
would have to do it prior to applying this function.

Also, as I'm new in R (coming from SAS) I don't know how well R will handle relatively large data sets (e.g. 1/2 million observations on 40 variables).

I don't have the answer to your first question but I routinely work with a dataset that is several times that large using the Design (and now) the rms packages. (You do need to have sufficient physical memory, but it is not R that is the limiting factor.)

--

David Winsemius, MD
Heritage Laboratories
West Hartford, CT

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