On Sun, 17 Oct 2004, Kuan-Ta Chen wrote:

Hi, all:

I find survreg {survival} has provided many distributions such as weibull,
lognormal, etc. But I wonder why it doesn't have the support for gamma
distribution since it should be a good distr. in lifetime analysis. Can
anybody figure out the reason?

Presumably the actual reason is because Terry Therneau didn't need to use the Gamma model. However, all the distributions in survreg are location-scale families, which the Gamma is not, so the basic algorithm would have to be different.


I've tried to implement the likelihood function of progressively censored
data for gamma distr. and use optim() to solve the paramemters. The
log-likelihood function L contains some integrations.

It shouldn't have to: we do have pgamma() built in (and digamma, trigamma, etc for derivatives).


                                                        I use tryCatch() to
capture the error when integration lead to divergence and return Inf.
But if consequent two calls to the objective function return Inf, optim()
will raise errors:

Error in optim(c(ga, 1/la), fr, method = "BFGS") :
       non-finite finite-difference value [1]

What can I do except for choosing better initial values?

Choose better initial values. You should be able to get quite good initial values for regression coefficients by using survreg on a lognormal distribution, since Gamma and lognormal distributions agree pretty well except in the extreme tails. You could then try getting the shape parameter by matching the variance of the Gamma to the variance of the fitted lognormal.


The last question, by its name "survreg", survreg does its job by
regression,
but why p.75 in Tableman, Kim (2004) said that "We use the S function
survReg to fit parametric models (with the MLE approach)...". Does survreg
use regression or MLE approach?

Its job *is* regression. It uses maximum likelihood to fit a regression model.


        -thomas

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