R2.3.0, WinXP. I am trying to fit the model
Y(t) = C1*exp(-exp(a)*t) + C2*exp(-exp(b)*t) - (C1+C2)*exp(-exp(c)*t) to some pharmacokinetic data. The data derives from a single oral dose of a drug. Does anyone know how to use peeling and/or other methods to obtain good starting estimates of the parameters in the triexponential? The book "Mixed Effects Models in S and SPLUS" describes self-starting models for the biexponential and first-order one-compartment PK models, but not for the triexponential. Much thanks in advance, Greg ______________________________________________ R-help@stat.math.ethz.ch mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide! http://www.R-project.org/posting-guide.html