Feng,

You say you are interested in the relationship between two variables, so the 
quantity you want to assess is something that describes that relationship.  
Usually that is the regression slope.

A much more serious problem is: how are you going to generate random 
permutations that honor the spatial correlation implicit in a SAR model?  You 
can not simply permute X variables, Y variables, or residuals because 
permutation assumes exchangability, a slightly more general version of 
independence.  You might consider toroidal rotations, but that makes other 
assumptions (e.g. 1st order stationarity) Pesarin has been developing 
permutation tests for complex data (see his book with that title).  I do not 
know whether he has considered data with a SAR structure.

Best,
Philip Dixon

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