This definitely looks like something. Thanks, Matt! Cheers,
Luiz 2013/11/11 Matt Pennell <mwpenn...@gmail.com> > Hi Luiz, > > > Yes, non-random sampling of traits, if not taken into account will > certainly bias the estimation of the transition parameters. Methods for > addressing this have been developed by Rich FitzJohn and colleagues > http://sysbio.oxfordjournals.org/content/58/6/595.short (this was > discussed in the context of state dependent diversification but also > applies to regular Mk models, which is just a special case of the BiSSE > model). > > I am sure there are potentially interesting follow-ups one could do here. > > cheers, > matt > > On Mon, Nov 11, 2013 at 9:52 AM, Luiz Max Carvalho < > luizepidemiolo...@gmail.com> wrote: > >> Dear all, >> >> Suppose you have observed K discrete traits for a phylogeny with N tips. >> For some reason, you think your trait sampling is not random, i.e., it may >> be biased towards some particular K's, for example because they're easier >> to sample. >> >> I imagine this will introduce some bias in the estimation of the >> infinitesimal rate matrix of the Markov model of trait evolution (Q). I >> would like to address this question in a more mathematically precise way. >> Have anyone heard of a study addressing these issues so far, both >> mathematically or using simulation studies? >> >> Thanks in advance. >> >> All the best, >> >> Luiz >> >> >> -- >> Luiz Max Fagundes de Carvalho, IC, Programa de Computação Científica >> (PROCC), Fundação Oswaldo Cruz, Rio de Janeiro, Brasil. >> >> https://www.researchgate.net/profile/Luiz_Fagundes_de_Carvalho/?ev=prf_info >> >> [[alternative HTML version deleted]] >> >> >> _______________________________________________ >> R-sig-phylo mailing list - R-sig-phylo@r-project.org >> https://stat.ethz.ch/mailman/listinfo/r-sig-phylo >> Searchable archive at >> http://www.mail-archive.com/r-sig-phylo@r-project.org/ >> > > -- Luiz Max Fagundes de Carvalho, IC, Programa de Computação Científica (PROCC), Fundação Oswaldo Cruz, Rio de Janeiro, Brasil. https://www.researchgate.net/profile/Luiz_Fagundes_de_Carvalho/?ev=prf_info [[alternative HTML version deleted]]
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